FORMULATION AND ANTIBACTERIAL TEST OF STAR ANISE EXTRACT (Illicium verum Hook.F) AS A HAND SANITIZER

Puspita, Dhanang; Ardhiawati, Eli; Desi, Desi

doi:10.31289/biolink.v7i1.3416

Cited by 3 publications

(4 citation statements)

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“…In 1998, Sy and Brown isolated novel lignans from anise leaves (98-102 and 105-107) [66], and later these compounds were also found in anise fruits [67,69]. The compounds verimol A (98) and harmandianone (92) showed concentration-dependent significant inhibition of lipopolysaccharide-induced tumour necrosis factor production in RAW264.7 cells [69]. Compounds 96, 97, 103, 104, 108, 111 and 112 are known lignan-like compounds that are found in anise [67,73].…”

Section: Phenylpropanoidsmentioning

confidence: 99%

“…For instance, Aceh curry, Rendang Minang, Javanese cuisines and Balinese cuisines employ star anise. In northern China, star anise is one of the most popular seasonings, and it can be used directly in a variety of food preparations such as stewing, boiling, pickling, brining and soaking, or it can be processed into a five-spice seasoning powder [92]. Star anise extracts have the advantages of being natural, non-toxic and harmless, and they are usually used in the food industry to produce various food flavors.…”

Section: Modern and Traditional Uses Of Star Anisementioning

confidence: 99%

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A Comprehensive Review of the Pharmacology, Chemistry, Traditional Uses and Quality Control of Star Anise (Illicium verum Hook. F.): An Aromatic Medicinal Plant

Zou,

Huang,

Zhang

et al. 2023

Molecules

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Illicium verum Hook. F., also known as star anise, is one of the most important plants of the genus Anise in the family Magnoliaceae. I. verum not only has the functions of warming Yang, dispersing cold, regulating Qi and relieving pain but can also be used as a condiment to increase flavor as well as reconcile and remove fish smells. Currently, 201 chemical constituents have been identified from star anise; among these, star anise oil and shikimic acid are the two most widely used and studied chemical components in star anise, with the oil accounting for a large proportion of the total. This review integrates, classifies and updates studies related to the botany, pharmacology, phytochemistry, traditional and modern uses and quality control of star anise, with a special reference to its phytochemical composition and pharmacological activity. It will provide a reference for further research on this important medicinal plant. In addition, the broad applications and research profiles of star anise essential oil and shikimic acid are highlighted. Our review indicates that the research prospects regarding star anise are very broad and worthy of further investigation.

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Section: Phenylpropanoidsmentioning

confidence: 99%

Section: Modern and Traditional Uses Of Star Anisementioning

confidence: 99%

A Comprehensive Review of the Pharmacology, Chemistry, Traditional Uses and Quality Control of Star Anise (Illicium verum Hook. F.): An Aromatic Medicinal Plant

Zou,

Huang,

Zhang

et al. 2023

Molecules

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“…Dimana hasil dari penelitian ini didapatkan rentang nilai rata-rata pH sediaan ada pada 8,67-9,80 yang dimana masuk kedalam kategori basa lemah. Seharusnya sediaan spray gel yang diformulasikan memiliki kisaran pH sesuai dengan pH kulit yakni pH 4,5-6,5 sehingga tidak menimbulkan efek negatif pada kulit, dikarenakan sediaan ini memiliki pH tinggi, maka berpotensi akan berpengaruh pada elastisitas kulit serta menyebabkan kulit licin dan cepat kering [13].…”

Section: Hasil Dan Pembahasanunclassified

Skrining Fitokimia dan Optimasi Basis Spray Gel Ekstrak Etanol Kulit Bawang Putih (Allium sativum L.) sebagai Anti Jerawat

Bandu,

Almeida,

Rijai

2023

Proc. Mul. Pharm. Conf.

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Spray gel is topical pharmaceutical preparations that can last long when sprayed on the skin. Because without physical contact, this preparation can reduce waste and the risk of developing skin diseases. The purpose of this study are determine the secondary metabolite content of garlic skin extract and obtain the optimal spray gel base. This study begins with the extraction of samples using 70% ethanol. Then qualitative phytochemical screening was conducted. Spray gel base optimization was carried out by varying the concentration of carbopol where F1(0,1%), F2(0,2%) and F3(0,3%) were then evaluated. The results of this study are garlic skin extract contains alkaloids, flavanoids, saponins and tannins. While the results of the base evaluation are in the organoleptic test all bases form are slightly cloudy in color, odorless and liquid, not sticky and has no air bubbles. All base formulas have been homogeneous, attached and spread, the range of the pH are 8.67-9.80 and the results of the viscosity test is range of average viscosity are 33.33-780 dPa.s. In this study, it can be concluded that garlic skin extract contains alkaloid, flavanoid, saponin and tannin that have potential as anti acne and the optimum carbopol concentration for spray gel base is 0,2%. Keywords: Phytochemical Screening, Allium sativum L., Spray Gel, Anti Acne Abstrak Spray gel termasuk kedalam sediaan topikal farmasi yang dapat bertahan lama ketika disemprotkan pada kulit, karna tanpa adanya kontak fisik sediaan ini dapat mengurangi limbah dan risiko terkena penyakit kulit seperti jerawat. Tujuan dari penelitian ini adalah untuk mengetahui kandungan metabolit sekunder dari ekstrak etanol kulit bawang putih dan mendapatkan basis optimal spray gel. Penelitian ini diawali dengan ekstraksi sampel menggunakan pelarut etanol 70%. Kemudian dilakukan skrining fitokimia secara kualitatif. Optimasi basis spray gel dilakukan dengan memvariasikan konsentrasi bahan pembentuk gel (karbopol) dimana F1(0,1%), F2(0,2%) dan F3(0,3%) yang kemudian dievaluasi. Hasil dari penelitian ini adalah ekstrak kulit bawang putih mengandung alkaloid, flavanoid, saponin dan tanin. Sedangkan hasil dari evaluasi basis adalah pada uji organoleptik dari semua basis didapatkan sediaan berwarna agak keruh, tidak berbau dan berbentuk cairan, tidak lengket serta tidak memiliki gelembung udara. Semua formula basis telah homogen, melekat dan menyebar, memiliki pH dengan rentang 8,67-9,80 dan hasil dari uji viskositas didapatkan hasil berupa rata-rata kekentalan sediaan 33,33-780 dPa.s. Pada penelitian ini dapat disimpulkan bahwa ekstrak etanol kulit bawang putih mengandung senyawa alkaloid, flavanoid, saponin dan tanin yang berpotensi sebagai anti jerawat serta konsentrasi karbopol yang optimum untuk sediaan spray gel ekstrak etanol kulit bawang putih adalah 0,2%. Kata Kunci: Skrining Fitokimia, Allium sativum L., Spray Gel, Anti Jerawat

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“…Modern pharmacological investigations demonstrated that I. verum possessed antiviral, , antioxidant, , antitumor, , antibacterial, , insecticidal, , anti-inflammatory, , analgesic, and neuroprotective activities. Previous phytochemical studies on I.…”

Section: Introductionmentioning

confidence: 99%

Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

Xia

et al. 2022

J. Agric. Food Chem.

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Illicium verum Hook.f. (Chinese star anise), a known Chinese traditional spice, is commonly applied in Chinese cuisine and cooking in Southeast Asia. As a kind of medicinal and edible resource, the fruit of I. verum has attracted great attention for its chemical constituents and physiological activities. In this work, the phytochemical study of the fruits of I. verum led to the isolation and identification of 20 compounds, including 6 new lignans and phenylpropanoids (1–6) and 14 known ones (7–20). Their structures were characterized by extensive analysis of spectroscopic data (IR, UV, high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), one-dimensional (1D) and two-dimensional (1D) NMR), electronic circular dichroism (ECD) calculation, and by comparison with literature data. Meanwhile, all compounds (1–20) were evaluated for their antiviral and antioxidant activities. Especially, compound 7 [(−)-bornyl p-coumarate] showed strong antiviral activities against influenza virus A/Puerto Rico/8/34 H1N1 (PR8) with an IC50 value of 1.74 ± 0.47 μM, which is much better than those of Tamiflu (IC50 = 10.01 ± 0.92 μM) and ribavirin (IC50 = 10.76 ± 1.60 μM). The antiviral activity against PR8 of compound 7 was reported for the first time, which was sufficiently confirmed by cell counting kit 8 (CCK-8), cytopathic effect (CPE) reduction, and immunofluorescence assays. In this study, the discovery of antiviral and antioxidant components from the fruits of I. verum could benefit the further development and utilization of this plant.

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FORMULATION AND ANTIBACTERIAL TEST OF STAR ANISE EXTRACT (Illicium verum Hook.F) AS A HAND SANITIZER

Cited by 3 publications

References 0 publications

A Comprehensive Review of the Pharmacology, Chemistry, Traditional Uses and Quality Control of Star Anise (Illicium verum Hook. F.): An Aromatic Medicinal Plant

A Comprehensive Review of the Pharmacology, Chemistry, Traditional Uses and Quality Control of Star Anise (Illicium verum Hook. F.): An Aromatic Medicinal Plant

Skrining Fitokimia dan Optimasi Basis Spray Gel Ekstrak Etanol Kulit Bawang Putih (Allium sativum L.) sebagai Anti Jerawat

Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

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