Formulation and Antibacterial Activity of Averrhoa bilimbi L. Fruits Extract in Vegetable Oil-Based Liquid Hand Soap

Hayati, Rima; Sari, Amelia; Hanum, Faridah; Nabilah, Nada; Earlia, Nanda; Lukitaningsih, Endang

doi:10.60084/mp.v1i1.35

Cited by 6 publications

(6 citation statements)

References 27 publications

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“…Proses tersebut berlangsung selama 5 x 1440 menit. Lalu dipekatkan dengan sebuah alat bernama rotari evaporator sampai bobot tetap (Hayati et al, 2023).…”

Section: Pembuatan Ekstrak Etanol Buah Malaka (Phyllanthus Emblica L)unclassified

FORMULASI DAN UJI ANTIOKSIDAN SEDIAAN FACE MIST DARI EKSTRAK ETANOL BUAH MALAKA (Phyllanthus emblica L.) SEBAGAI PELEMBAB WAJAH

Febriani,

Axyvia,

Salman

2024

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Antioksidan sebagai penangkal radikal bebas sangat diperlukan oleh tubuh. Sumber antioksidan bisa diperoleh secara alami dan mudah dijumpai di sekitar kita. Salah satu sumber antioksidan alami adalah buah malaka (Phyllanthus emblica L.) karena mengandung flavonoid. Buah malaka diformulasikan pada sediaan face mist karena mudah dibawa dan mudah diserap pada kulit. Penelitian ini menggunakan metode eksperimental dimana buah malak diaplikasikan sebagai zat aktif pada sediaan face mist. Adapun uji yang dilakukan terhadap sediaan face mist yaitu uji mutu fisik sediaan, kelembaban dan nilai aktivitas antioksidan. Hasil mutu fisik sediaan menunjukkan keberhasilan karena telah memenuhi persyaratan. Sediaan face mist stabil dalam suhu yang diaplikasikan, pH yang diperoleh sesuai dengan pH kulit yaitu 5,1 – 5,6 dan tidak menimbulkan efek kemerahan pada kulit. Viskositas, daya sebar dan waktu kering sediaan face mist sebesar 4.00 – 8.00 mPa.s, 5 – 7 cm dan 3:05 – 4:02 menit. Persen kelembaban tertinggi dimiliki oleh Formulasi 3 yaitu sebesar 25,01% dan nilai aktivitas antioksidan tertinggi dimiliki oleh Formulasi 2 yaitu sebesar 18,84 μg/mL.

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“…Proses tersebut berlangsung selama 5 x 1440 menit. Lalu dipekatkan dengan sebuah alat bernama rotari evaporator sampai bobot tetap (Hayati et al, 2023).…”

Section: Pembuatan Ekstrak Etanol Buah Malaka (Phyllanthus Emblica L)unclassified

FORMULASI DAN UJI ANTIOKSIDAN SEDIAAN FACE MIST DARI EKSTRAK ETANOL BUAH MALAKA (Phyllanthus emblica L.) SEBAGAI PELEMBAB WAJAH

Febriani,

Axyvia,

Salman

2024

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“…Diarrhea can stem from either infectious or noninfectious factors, with infection being the predominant cause. Bacterial, parasitic, and viral infections are the most prevalent contributors to infectious diarrhea [8,9]. Diarrhea also may result from malabsorption, inflammatory bowel disease, food poisoning, or the effects of medications [10,11].…”

Section: Introductionmentioning

confidence: 99%

Probiotics and Their Role in Decreasing Diarrhea Prevalence in the Elderly Population: A Comprehensive Meta-Analysis

Muliana,

Mulia,

Suardi

et al. 2024

Malacca Pharm.

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Diarrhea is an atypical state of the digestive system characterized by a soft or watery texture in bowel movements. Antibiotic-related diarrhea is common in the elderly due to extensive antibiotic use. Probiotics are vital microorganisms that support the intestinal flora and reduce bacterial colonization in the intestinal wall. This study aimed to assess the effectiveness, type, and dose of probiotics for diarrhea in the elderly. A systematic review with meta-analysis was conducted using PubMed, ScienceDirect, and Google Scholar. Seven records with a total of 2,087 participants were included. A quantitative analysis was carried out using Review Manager version 5 software. A meta-analysis was conducted to assess the frequency of diarrhea. The results showed that using probiotics significantly reduced the risk of antibiotic-related diarrhea 0.53 times compared to the placebo administration (OR 0.53; CI 95% 0.29 to 0.98; I2 = 70%). The type of probiotics frequently given was the genera of Lactobacillus, Bifidobacterium, and Streptococcus, with consumption durations varying from 3 days to a maximum of 4 weeks. The dose of probiotics ranged from a minimum of 1.0 × 10⁶ CFU to a maximum dose of 2 × 10¹⁰ CFU. To conclude, probiotic administration is more effective than placebo in reducing the risk of antibiotic-related diarrhea in the elderly.

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“…The increasing incidence of resistance among pathogenic microorganisms against antimicrobial agents is primarily attributed to the inappropriate use of these agents in treating various infectious diseases [12]. These conditions have encouraged many researchers to explore and discover new antimicrobial agents by investigating the potential of plants and other natural resources [13,14].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Properties of Medicinal Plants in the Lower Area of Ie Seu-um Geothermal Outflow, Indonesia

Fakri,

Harahap,

Muhni

et al. 2023

Malacca Pharm.

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The lower area of the Ie Seu-um manifestation, located in Ie Seu-um village, Aceh Besar District, harbors several medicinal plants that exhibit potential for the treatment of infectious diseases. This study aims to assess the secondary metabolite content and in vitro antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans of medicinal plants inhabiting the geothermal region. Medicinal plants, namely Pluchea indica (L.) Less., Acrostichum aureum L., Acacia mangium L., and Calotropis gigantea (L.) Dryand., were collected within a range of 100-150 meters from the hot springs in the lower area. Methanol extracts of these medicinal plants underwent phytochemical screening and were tested for antimicrobial activity using the Kirby-Bauer disc diffusion method at a concentration of 50%. The results of phytochemical screening demonstrated positive variations in alkaloids, flavonoids, saponins, steroids, triterpenoids, and tannins for each medicinal plant. The antimicrobial activity of the methanol extracts noticeably inhibited the growth of S. aureus compared to E. coli and C. albicans. The largest inhibition zones were observed for the leaf part of A. mangium (12.70 ± 2.30 mm) against S. aureus, the aerial part of A. aureum (11.57 ± 2.01 mm) against E. coli, and the aerial part of P. indica (9.89 ± 1.11 mm) against C. albicans. Based on the research findings, medicinal plants originating from the lower area of the Ie Seu-um manifestation exhibit potential as antimicrobial agents, particularly against gram-positive bacteria.

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Formulation and Antibacterial Activity of Averrhoa bilimbi L. Fruits Extract in Vegetable Oil-Based Liquid Hand Soap

Cited by 6 publications

References 27 publications

FORMULASI DAN UJI ANTIOKSIDAN SEDIAAN FACE MIST DARI EKSTRAK ETANOL BUAH MALAKA (Phyllanthus emblica L.) SEBAGAI PELEMBAB WAJAH

FORMULASI DAN UJI ANTIOKSIDAN SEDIAAN FACE MIST DARI EKSTRAK ETANOL BUAH MALAKA (Phyllanthus emblica L.) SEBAGAI PELEMBAB WAJAH

Probiotics and Their Role in Decreasing Diarrhea Prevalence in the Elderly Population: A Comprehensive Meta-Analysis

Antimicrobial Properties of Medicinal Plants in the Lower Area of Ie Seu-um Geothermal Outflow, Indonesia

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