FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN SEDIAAN SERUM EKSTRAK ETANOL BIJI KOPI HIJAU (Coffea canephora pierre)

Abstract

The use of natural ingredients in cosmetics to prevent premature aging caused by exposure to ultraviolet radiation is becoming a popular trend in Indonesia. The bad effects of exposure to ultraviolet radiation can cause the skin to lose its elasticity and premature aging which is characterized by sagging, thinning, dry skin, the appearance of black spots on the skin, hyperpigmentation, fine lines and wrinkles. One of the plants that can be used to make natural cosmetic ingredients is green coffee beans (Coffea canephora pierre), where green coffee beans contain alkaloids, tannins, phenolics, flavonoids, triterpenoids and glycosides which are believed to be antioxidant agents. Green coffee beans (Coffea canephora pierre) have poor solubility, so serum preparations were chosen to be able to deliver active compounds quickly and effectively to the skin. The method for checking antioxidant activity used in this research was carried out using the DPPH (2,2 -diphenyl-1-picrylhdrazil) method, while to determine the best serum formula, the physical evaluation method of the preparation was chosen in the form of organoleptic test, homogeneity test, pH, viscosity test, spreading power, and sticking power. In this research, the results showed that green coffee beans (Coffea canephora pierre) contain alkaloids, tannins, saponins, quinones, steroids/terpenoids and flavonoids. The best formula with the highest antioxidant activity value in F3 with an IC50 value of 17,302 ppm and each formulation of green coffee bean (Coffea canephora pierre) ethanol extract serum is stable in physical evaluation, so it can be concluded that green coffee bean extract serum can be used as a new agent for prevention of premature aging.