FORMULASI DAN UJI AKTIVITAS ANTIJAMUR SEDIAAN KRIM EKSTRAK METANOL KETEPENG CINA (Cassia alata L.) TERHADAP JAMUR Candida albicans

Rumayar, Ricky C.; Yamlean, Paulina V. Y.; Siampa, Jainer Pasca

doi:10.35799/pha.9.2020.30020

Cited by 4 publications

(9 citation statements)

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“…Pemanasan dilakukan pada suhu 70±50C karena suhu titik leleh tertinggi yaitu asam stearat dengan titik leleh 67-700C 6 . Propil paraben dan metil paraben berfungsi sebagai pengawet digunakan dalam bentuk kombinasi untuk meningkatkan efektifitas kerjanya 15 .…”

Section: Pembahasanunclassified

“…Kemudian fase minyak dan fase air dicampurkan dalam satu wadah. Krim dibuat dengan mencampurkan dua fase yaitu fase minyak dan fase air secara bersamaan pada suhu 75±50C di dalam satu wadah diaduk terus menerus hingga terbentuk massa krim 15 . Massa krim tersebut diaduk menggunakan head stirrer dengan kecepatan 300 rpm dengan tujuan dihasilkan sediaan yang homogen dengan tekstur lembut 11 F1: Formula hand cream dengan Parafin cair 9%; F2: Formula hand cream dengan Parafin cair 10%; F3: Formula hand cream dengan Parafin cair 9%; PS : Putih Susu; L: Lembut; BKK : Bau Khas Kemangi.…”

Section: Pembahasanunclassified

“…Hasil Uji Tipe Emulsi 15 . Setelah membentuk massa krim yang baik, sediaan didinginkan hingga suhu di bawah 300C.…”

Section: Formulaunclassified

“…Hasil evaluasi organoleptis (Tabel 2 dan Gambar 1), didapatkan bahwa hasil dari ketiga formula sediaan hand cream minyak atsiri daun kemangi tidak mengalami perubahan baik pada warna, tekstur, maupun bau. Hal tersebut menunjukkan bahwa sediaan hand cream minyak atsiri daun kemangi memiliki stabilitas yang baik secara fisik 15 .…”

Section: Formulaunclassified

“…Hasil evaluasi homogenitas (Tabel 3), didapatkan bahwa sediaan hand cream minyak atsiri daun kemangi tidak terdapat tekstur berpasir, hal tersebut menunjukan sediaan memiliki homogenitas yang baik. Hal tersebut sesuai dengan penelitian sebelumya yang dilakukan oleh Rumayar dkk (2020), dimana sediaan krim yang homogen ditunjukan dengan tidak terlihatnya tekstur berpasir pada krim 15 . Hasil yang homogen dalam sediaan menandakan bahwa sediaan hand cream minyak atsiri daun kemangi memiliki nilai yang konstan dimana tidak ada pengaruh dari variasi konsentrasi dan waktu penyimpanan terhadap homogenitas bentuk sediaan 12 .…”

Section: Formulaunclassified

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Formulation of Hand Cream Essential Oil of Basil (Ocimum basilicum) Leaves

Tanjung¹,

Akmal²,

Virginia³

2022

IJPST

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Basil (Ocimum basilicum) leaf essential oil contains terpenoid compounds that have antibacterialactivity. This study aims to obtain hand cream preparations of basil essential oil, as well as to determinethe effect of concentration variation of liquid paraffin on the results of the evaluation of the preparation.In this study, three formulations of hand cream preparations of basil essential oil were made withthree variations in the concentration of liquid paraffin, namely F1 (9%), F2 (10%), and F3 (11%).Furthermore, the preparation was evaluated for 28 days at room temperature (15-300C) and humidity(60-80%) which included organoleptic, pH, viscosity, homogeneity, spreadability, and type of emulsion.The results showed that formulas F1, F2, and F3 met all the requirements of organoleptic, pH, viscosity,homogeneity, spreadability, and type of emulsion. The results of the statistical analysis showed thatvariations in liquid paraffin concentrations had a significant effect (p<0.05) on the evaluation ofviscosity and did not significantly affect the evaluation of organoleptic, evaluation of pH, evaluation ofhomogeneity, evaluation of spreadability, and evaluation of emulsion type.

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Section: Pembahasanunclassified

“…Hasil Uji Tipe Emulsi 15 . Setelah membentuk massa krim yang baik, sediaan didinginkan hingga suhu di bawah 300C.…”

Section: Formulaunclassified

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Formulation of Hand Cream Essential Oil of Basil (Ocimum basilicum) Leaves

Tanjung¹,

Akmal²,

Virginia³

2022

IJPST

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Review of Traditional First Aid for Burn Injuries in the 21st Century

Hafizurrachman,

Menna,

Lesmana

2023

Ann Plast Surg

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Introduction This review aims to investigate data on traditional burn first aid materials used in different countries. Methods A systematic search was performed through 8 databases for studies on traditional burn first aid published in the 21st century. Data regarding study demographics, burn first aid, first aid materials, water irrigation, and source of knowledge were summarized, and the use of each material was discussed. Results A total of 28 studies including 20,150 subjects were identified. An average of 29% of the study population applied water irrigation, whereas 46% used various traditional materials, and 30% did not administer first aid. People with higher education and socioeconomy class tend to choose correct first aid actions. Discussion The single best treatment as burn first aid is cool-water irrigation. Despite that, various other materials have been used, most of which are not suitable for first aid. Some materials possess healing abilities and can be used as wound dressing, whereas others are harmful. Inappropriate materials are mostly used in underdeveloped regions lacking water access and hygiene. Mass media and community knowledge have a large influence in burn first aid practices. Conclusion Raising public health awareness on burn first aid is crucial along with providing the people access to water, basic hygiene, and health care.

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Antimicrobial Test of Telang Flower Extract (Clitoria ternatea L.) against the Growth of Candida albicans

Wijaya¹,

Destiawan²,

Cahyariza³

2023

J. Prisma. Sains

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Candidiasis is an acute and subacute fungal infection caused by the Candida group, especially Candida albicans. Infectious diseases due to microbes can be treated using modern drugs, namely antifungals. In some cases, antimicrobials often develop resistance due to improper administration. The occurrence of such resistance encourages further research on new active ingredients that can be used as antimicrobial alternatives, especially from plant sources containing flavonoids. The purpose of this study is to determine the effect of antimicrobial content of ethanol extract 70% of Telang flowers on the growth of C. albicans. This research is a laboratory experimental research with post test control group design only method. Determination of antimicrobial activity is carried out by the pitting method. Telang flower extract that has been diluted with 10% DMSO, taken as much as 30µl then dripped into the well. Positive control using antimicrobial ketocenazole and negative control using DMSO 10% which was dripped on the well as much as 30µl. Based on the results of observations, the inhibition zone is only formed in positive control with an average of 15.5 + 0.4 mm. The results of ethanol extract of 70% Telang flowers that have been conducted did not show antimicrobial activity against fungal growth C. albicans. The absence of this inhibitory zone is due to the unknown concentration of active compounds of Telang flowers that are responsible as antimicrobials, so it is necessary to conduct research on the search for concentrations of active compounds that have the ability as antimicrobials.

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FORMULASI DAN UJI AKTIVITAS ANTIJAMUR SEDIAAN KRIM EKSTRAK METANOL KETEPENG CINA (Cassia alata L.) TERHADAP JAMUR Candida albicans

Cited by 4 publications

References 0 publications

Formulation of Hand Cream Essential Oil of Basil (Ocimum basilicum) Leaves

Formulation of Hand Cream Essential Oil of Basil (Ocimum basilicum) Leaves

Review of Traditional First Aid for Burn Injuries in the 21st Century

Antimicrobial Test of Telang Flower Extract (Clitoria ternatea L.) against the Growth of Candida albicans

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