Abstract:Clove extract (Syzygium aromaticum) contains eugenol 70% -85%. The clove extract is formulated in the form of mucoadhesive buccal patches. The purpose of this study was to obtain the formulation for mucoadhesive buccal patches having optimal stability that has good pharmaceutic properties and also effectively inhibits the Streptococcus mutans bacteria. The research design used was laboratory experimental research. The mucoadhesive buccal patches with a combination of PVP and HPMC polymers made in 5 formulas ba… Show more
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