The hydrological series of the minimum annual discharges of the Instruch River (hydrological gauging station Ulyanovo, Kaliningrad region) was studied. The values of the minimum discharge rates were processed in the Mathcad environment. The characteristics of the minimum discharges (average and minimum annual, minimum 5-, 10- and 30-day discharges) of the Instruch River in 1901-1912 and 2008-2020 are determined. A comparative analysis of the characteristics of the minimum annual discharges of the river Instruch for the indicated periods.