Formation of thioglucoside single crystals by coherent molecular vibrational excitation using a 10-fs laser pulse

Iwakura, Izumi; Komori-Orisaku, Keiko; Hashimoto, Sena; Akai, Shoji; Kimura, Kenta; Yabushita, Atsushi

doi:10.1038/s42004-020-0281-6

Cited by 7 publications

(2 citation statements)

References 24 publications

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“…Since then, a considerable number of studies have been reported with various types of chemical compounds and by employing an array of laser systems whose properties/parameters including time duration (continuous, femtosecond, picosecond, nanosecond regime), − field polarization (linear, circular and elliptical), − wavelength (UV–vis–IR), or intensity (ionizing, nonionizing), − were altered to control primary nucleation. However, despite the remarkable scientific progress, the underlying mechanism behind the laser-induced nucleation still remains unclear.…”

Section: Introductionmentioning

confidence: 99%

Influence of Laser Parameters and Experimental Conditions on Nonphotochemical Laser-Induced Nucleation of Glycine Polymorphs

Irimia

Shirley

Garg

et al. 2020

Crystal Growth & Design

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Nonphotochemical laser-induced nucleation (NPLIN) is a promising primary nucleation control method, yet its underlying mechanism remains elusive. To contribute to the discussion on whether the polarization of laser irradiation in NPLIN experiments influences the polymorphic outcome, we revisit NPLIN experiments with aqueous glycine solutions with supersaturations ranging between S = 1.5 and S = 1.7 irradiated by nanosecond pulses (∼7 ns) of near-infrared wavelength (1064 nm). Systematically altering laser light excitation properties, including the number of pulses and type of polarization, we quantified the nucleation kinetics and characterized the polymorphic form that crystallized upon laser irradiation. Due to the stochasticity of the nucleation process, a large number of samples (>100 per each experimental point) were studied under carefully controlled experimental conditions such as the ambient temperature, cooling rate, and aging period. We observed significant differences among laser-irradiated, spontaneously nucleated, and crash-cooled samples in terms of nucleation kinetics and polymorphic form. This result indicates that laser irradiation provides a different polymorph-forming pathway in comparison to crash-cooling and spontaneous nucleation. However, no clear dependence between the polymorphic form and the polarization of laser irradiation is observed. We discuss our results in the context of previous reports supported thorough quantification of sample heating in NPLIN experiments.

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Section: Introductionmentioning

confidence: 99%

Influence of Laser Parameters and Experimental Conditions on Nonphotochemical Laser-Induced Nucleation of Glycine Polymorphs

Irimia

Shirley

Garg

et al. 2020

Crystal Growth & Design

View full text Add to dashboard Cite

show abstract

“…Pulsed laser-induced crystallization of organic molecules has been known since 1996 by Garetz et al and has been advanced in the early 2000s by Okutsu et al , and Yoshikawa et al , Mainly small molecules, − amino acids, and small proteins have been crystallized with pulsed lasers so far.…”

Section: Introductionmentioning

confidence: 99%

Enhanced Predictability of Urea Crystallization by an Optimized Laser Repetition Rate

Geiger,

Howard,

MacKinnon

et al. 2024

Crystal Growth & Design

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Laser-induced crystallization is a novel alternative to classical methods for crystallizing organic molecules but requires a judicious choice of experimental parameters for the onset of crystallization to be predictable. This study investigated the impact of the laser repetition rate on the time delay from the start of the pulsed laser illumination to the initiation of crystallization, the socalled induction time. A supersaturated urea solution was irradiated with near-infrared (λ = 1030 nm) laser pulses of pulse duration τ = 5 ps at a pulse energy of approximately E = 340 μJ while varying the repetition rate from 10 to 20,000 Hz. The optimal rate discovered ranged from 500 Hz to 1 kHz, quantified by the measured induction time (median 2−5 s) and the mean probability of inducing a successful crystallization event (5 × 10 −2 %). For higher repetition rates (5−20 kHz), the mean probability dropped to 3 × 10 −3 %. The reduced efficiency at high repetition rates is likely due to an interaction between an existing thermocavitation bubble and subsequent pulses. These results suggest that an optimized pulse repetition rate can be a means to gain further control over the laser-induced crystallization process.

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Quantum Coherence Effect in the Interaction of Light and Molecules

Song,

Qin,

Dong

et al. 2024

Laser & Photonics Reviews

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Understanding the quantum coherence effects is crucial for their promising applications, such as engineering artificial photosynthesis, manipulating chemical reactions, and designing coherence‐based functional devices. Considering that a molecule is the smallest unit that can exist independently and maintain its physical and chemical properties, investigating the quantum coherence effects of molecules is of great significance in understanding their features. In this case, exploring quantum coherence effects in the interaction of light and molecules has been one of the leading topics. This review presents an overview of state‐of‐the‐art spectroscopic techniques and deep insights into molecular quantum coherence effects. It also offers prospects for future advancement. First, the history of development and origins of quantum coherence effects are briefly introduced in molecules. Then, the principle and exciting experimental progress of sophisticated techniques for investigating molecular quantum coherence effects are discussed. Late, molecular quantum coherence effects and their promising applications in various areas have been evaluated. Finally, the challenges and potential solutions are look ahead for studying the effects of quantum coherence on molecules. This review may offer some guidance to boost the understanding and employing the molecular quantum coherence effects.

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Formation of thioglucoside single crystals by coherent molecular vibrational excitation using a 10-fs laser pulse

Cited by 7 publications

References 24 publications

Influence of Laser Parameters and Experimental Conditions on Nonphotochemical Laser-Induced Nucleation of Glycine Polymorphs

Influence of Laser Parameters and Experimental Conditions on Nonphotochemical Laser-Induced Nucleation of Glycine Polymorphs

Enhanced Predictability of Urea Crystallization by an Optimized Laser Repetition Rate

Quantum Coherence Effect in the Interaction of Light and Molecules

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