Formation of polyaniline layer on DNA by electrochemical polymerization

Bardavid, Yosef; Ghabboun, Jamal; Porath, Danny; Kotylar, Alexander B.; Yitzchaik, Shlomo

doi:10.1016/j.polymer.2008.03.014

Cited by 19 publications

(19 citation statements)

References 33 publications

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“…Deposition of PANI onto DNA is explained by template effect described in the literature [40,41,42]. Positively charged oligomers and protonated aniline molecules are accumulated onto phosphate residues of the DNA backbone.…”

Section: Resultsmentioning

confidence: 99%

Electrochemical DNA Sensors with Layered Polyaniline—DNA Coating for Detection of Specific DNA Interactions

Kulikova

Porfireva

Evtugyn

et al. 2019

Sensors

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A DNA sensor has been proposed on the platform of glassy carbon electrode modified with native DNA implemented between two electropolymerized layers of polyaniline. The surface layer was assembled by consecutive stages of potentiodynamic electrolysis, DNA drop casting, and second electrolysis, which was required for capsulation of the DNA molecules and prevented their leaching into the solution. Surface layer assembling was controlled by cyclic voltammetry, electrochemical impedance spectroscopy, atomic force, and scanning electron microscopy. For doxorubicin measurement, the DNA sensor was first incubated in the Methylene blue solution that amplified signal due to DNA intercalation and competition with the doxorubicin molecules for the DNA binding sites. The charge transfer resistance of the inner layer interface decreased with the doxorubicin concentration in the range from 1.0 pM to 0.1 μM (LOD 0.6 pM). The DNA sensor was tested for the analysis of spiked artificial urine samples and showed satisfactory recovery in concentration range of 0.05–10 μM. The DNA sensor developed can find application in testing of antitumor drugs and some other DNA damaging factors.

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Section: Resultsmentioning

confidence: 99%

Electrochemical DNA Sensors with Layered Polyaniline—DNA Coating for Detection of Specific DNA Interactions

Kulikova

Porfireva

Evtugyn

et al. 2019

Sensors

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“…Template effect of DNA added to the polymerization mixture was reported for various synthesis conditions [31][32][33][34][35][36][37][38]. However, to the best of our knowledge, PANI/DNA layers have not been used yet for detection of small intercalators.…”

Section: Introductionmentioning

confidence: 99%

Polyaniline–DNA based sensor for the detection of anthracycline drugs

Shamagsumova

Porfireva

Stepanova

et al. 2015

Sensors and Actuators B: Chemical

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“…The electropolymerization of aniline on both DNA monolayer and single poly(dG)poly(dC) DNA molecules, leading to the PANI-NFs, was reported [250]. The synthesis includes the formation of an electrostatic complex between the negatively charged DNA and positively charged anilinium ions, followed by electrochemical oxidation and polymerization of the anilinium ions on the DNA template.…”

Section: Electrochemical Template Methodsmentioning

confidence: 99%

Polyaniline Nanostructures

Ćirić‐Marjanović

2010

Nanostructured Conductive Polymers

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Polyaniline (PANI) is one of the most extensively studied conducting polymers because of its simple synthesis [1] and doping/dedoping chemistry [2], low cost, high conductivity, and excellent environmental stability. PANI has a wide applicability in rechargeable batteries [3], erasable optical information storage [4], shielding of electromagnetic interference [5], microwave-and radar-absorbing materials [6], sensors [7], indicators [8], catalysts [9], electronic and bioelectronic components [10], membranes [11], electrochemical capacitors [12], electrochromic devices [13], nonlinear optical [14] and light-emitting devices [15], electromechanical actuators [16], antistatic [17] and anticorrosion coatings [18]. Its electromagnetic and optical properties depend mostly on its oxidation state and degree of protonation [19]. The green emeraldine salt form of PANI is conducting ($1-10 S cm À1 for granular powders) [1]. It contains, depending on the synthetic route, variousunits (in the preceeding formulae B, Q and A À denote a benzenoid ring, quinonoid ring and dopant anion, respectively). The blue emer-The preparation of bulk quantities of conducting granular PANI is usually performed Nanostructured Conductive PolymersEdited by Ali Eftekhari by the oxidative polymerization of aniline with ammonium peroxydisulfate (APS) in an acidic aqueous solution (initial pH < 2.0) [1]. Colloidal PANI nanoparticles are prepared by dispersion polymerization of aniline in the presence of various colloidal stabilizers [20,21]. The average size of colloidal PANI nanoparticles decreases with increasing stabilizer/aniline ratio. PANI colloids often have nonspherical (rice grain, needle-like, etc.) core-shell morphology. The colloidal nanoparticle core most likely has a composite nature, i.e. it is composed of both the PANI and the incorporated stabilizer, while the shell is formed by the stabilizer. Nowadays, conducting PANI nanostructures are the focus of intense research owing to their significantly enhanced dispersibility and processability, and substantially improved performance in many applications, in comparison with granular and colloidal PANI [22][23][24][25][26][27]. The continuously growing interest in the study of zero-dimensional (0-D) (solid nanospheres), one-dimensional (1-D) (nanofibers (nanowires), nanorods (nanosticks), nanoneedles, rice-like nanostructures, nanotubes), two-dimensional (2-D) (nanoribbons (nanobelts), nanosheets (nanoplates, nanoflakes, nanodisks, leaf-like nanostructures), nanorings (cyclic nanostructures), net-like nanostructures), and three-dimensional (3-D) PANI nanostructures (hollow nanospheres, dendritic and polyhedral nanoparticles, flower-like, rhizoid-like, brain-like, urchin-like, and star-like nanostructures, etc.) has dramatically increased in recent years (Figure 2.1). The major focus of research has been the preparation, characterization, processing, and application of PANI nanofibers (PANI-NFs) and nanotubes (PANI-NTs). PANI-NFs are 1-D PANI nanoobjects of cylindrical profile with diameters ...

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Formation of polyaniline layer on DNA by electrochemical polymerization

Cited by 19 publications

References 33 publications

Electrochemical DNA Sensors with Layered Polyaniline—DNA Coating for Detection of Specific DNA Interactions

Electrochemical DNA Sensors with Layered Polyaniline—DNA Coating for Detection of Specific DNA Interactions

Polyaniline–DNA based sensor for the detection of anthracycline drugs

Polyaniline Nanostructures

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