Formation of interzonal interaction of cortical fields during verbal-mental activity

Ontogenetic Development of Neurophysiological Mechanisms Underlying Language Processing

“…An appropriate way to study patterns of cortical interactions is analysis of the spatiotemporal organization of brain activity oscillations. Currently, it is of no doubt that language processing relies on a widespread network of brain regions [1][2][3][4][5][20][21][22][23][24][25][26]. Great importance is also attached to the role of cortical networks and functional connections between different parts of the brain, in both adults and children [21,22,[27][28][29][30][31][32][33].…”

“…The essential role of joint activity of both cerebral hemispheres in providing speech was also revealed during the analysis of the violations of systemic brain activity organization in children with developmental speech disorders such as alalia, dysarthria, and stuttering [1,5,6,16].…”

“…In 12 children aged 3-4 years with motor alalia and 15 children aged 5-6 years with dysarthria were detected both significant differences in the nature and localization of violations of the systemic interaction of brain potentials and were revealed indicators of similarity (Figure 4) [16]. To specify the role of hemispheric interactions in pathogenesis of these verbal impairments, it is important to consider the data showing that in case of both alalia and dysarthria there were revealed two types of changes in systemic interaction of brain cortical biopotentials with the direction of these changes differing in the right and left hemispheres [1]. In all children with these types of verbal pathology, against the background of a decrease in EEG connections of one of the hemispheres, the interregional interaction of bioelectrical activity in the brain cortex also significantly exceeded the interaction in the contralateral hemisphere, as compared to the normative level; this was especially characteristic of children with dysarthria ( Figure 5).…”

“…A study of the functional interaction between various parts of the cerebral cortex (so-called functional connectivity) is of fundamental importance for understanding the neural basis of cognition [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. A growing number of studies that have appeared in the last decade testify the renewed interest in functional interactions among different brain parts, in both the background state and under cognitive activity [13,15].…”