Formation of hydroxyapatite on CaSiO3 powders in simulated body fluid

Siriphannon, Punnama; Kameshima, Yoshikazu; Yasumori, Atsuo; Okada, Kiyoshi; Hayashi, Shigeo

doi:10.1016/s0955-2219(01)00301-6

Cited by 187 publications

(144 citation statements)

References 18 publications

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“…Modified SBF (simulated body fluid) was prepared according to reference [27]. The materials for SBF were listed as follows: sodium chloride (AR, 99.5%; Aladdin Bio-Chem, China), sodium bicarbonate (AR, ≥99.8%; Aladdin), potassium chloride (AR, 99.5%; Aladdin), potassium dihydrogen phosphate (AR, 99%; Aladdin), magnesium chloride hexahydrate (AR, 98.0%; Aladdin), calcium chloride (AR, 96.0%; Aladdin), sodium sulphate (AR, 99%; Aladdin), tris(hydroxymethyl)aminomethane (≥99.9%; Aladdin), hydrochloric acid (1mol/L; Sinopharm) and standard pH solution (Sinopharm).…”

Section: Assessment Of Biodegradationmentioning

confidence: 99%

Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance

Chen

Zhang

Yang

et al. 2017

Ceramics International

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Section: Assessment Of Biodegradationmentioning

confidence: 99%

Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance

Chen

Zhang

Yang

et al. 2017

Ceramics International

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“…The ability to form a bioactive layer at the interface between material and living tissue was observed in 1969 and this phenomenon was defined as bioactivity 1 . Since the discovery of Bioglass  , which promotes a rapid osseointegration 2,3 , a great variety of bioactive materials for medical applications, such as glasses, glass-ceramics, ceramics and composites, have been developed 4,5 . The main requisites of a bioactive material are biocompatibility, appropriate mechanical properties and the ability to form an HA layer on its surface 6 .…”

Section: Introductionmentioning

confidence: 99%

Bioactive and Hemocompatible Calcium Sulphoaluminate Cement

et al. 2015

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“…Bioactive materials, such as hydroxyapatite (HA), can integrate well with living bone tissues by forming spontaneously a biologically active bone-like apatite layer on their surfaces [1][2][3][4]. HA shows excellent biocompatibility with hard skin and muscle tissues and can directly bond to the bone [5].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and bioactivity evaluation of nano-structured hydroxyapatite

Fathi¹,

Mortazavi²,

Hanifi³

et al. 2009

Computational Methods and Experiments in Materials Characterisation IV

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Due to its biocompatibility and bioactivity, hydroxyapatite (HA) has a wide range of applications in medical engineering cases, such as bone repair and bone tissue regeneration. The use of artificial HA with a similar structure and chemical composition to biological apatite could increase the durability of the HA inside the natural hard tissues. The aim of the present work was to synthesis nano-structured HA via different routs, the comparison of their characteristics and enhancement of the bioactivity of HA by controlling its crystallite size and chemical composition. Nano HA was prepared by mechanical activation and sol gel routs. The x-ray diffraction technique (XRD), Fourier transform infra red spectroscopy (FTIR) and transmission electron microscopy (TEM) were used to characterize the HA powder. The synthesized powder was soaked in simulated body fluid (SBF) for various periods of time in order to evaluate its bioresorbability and bioactivity after immersion in SBF. Atomic absorption spectroscopy (AAS) was used to determine the dissolution of calcium ions in the SBF media. Results showed that the prepared HA powder had a nanoscale structure with a size of 29 nm for the powder prepared by mechanical activation and 25 nm for the powder that was prepared by the sol gel method. The ionic dissolution rate of nano-structured powder was higher than conventional HA (with micro scale size) and was similar to biological apatite. It could be concluded that bioactivity behaviour of HA powder is affected by its crystallite size. Using the nano-structured HA powder with less than 50 nm crystallite size, the optimum bioactivity and bioresorbability would be achieved.

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Formation of hydroxyapatite on CaSiO3 powders in simulated body fluid

Cited by 187 publications

References 18 publications

Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance

Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance

Bioactive and Hemocompatible Calcium Sulphoaluminate Cement

Synthesis, characterization and bioactivity evaluation of nano-structured hydroxyapatite

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