Formation of hydridocobalt(iii) phthalocyanine by reaction of cobalt(ii) phthalocyanines with sodium borohydride and its reactions with antioxidant isoflavones

Phthalocyanine Metal Complexes in Catalysis

“…The reduction of substituted flavons and isoflavons with NaBH 4 catalyzed by CoPc’s has been described. These naturally occurring compounds possess significant biological activity, and their reduced metabolites have been extensively studied for their estrogenic, antifungal, and anticancer activity.…”

“…The proposed mechanism involves Co I Pc and hydrido HCo III Pc species. The same system reduced isoflavons with lower selectivity, although the cis-isomer was again a major product (Scheme ) …”

Metal Phthalocyanines Catalyzed Selective Organic Transformations: Recent Developments and Promising Future

“…Chauhan et al have utilized CoPc for the selective reduction of flavones and isoflavones with sodium borohydride as reducing agent [1,2]. The mechanistic study revealed the involvement of electron transfer mechanism through the formation of hydridocobalt (III) complex.…”