DOI: 10.5772/intechopen.89800
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Wei Chen, Ting-Ting Xie, Hong Zeng

Abstract: Staphylococcus epidermidis, member of the group of coagulase-negative staphylococci, belongs to an opportunistic pathogen. It is reported that the major pathogenicity of S. epidermidis is attributed to its biofilm formed on the surface of infected tissues, which enhances bacterial resistance to antibiotics. Thus, how to inhibit biofilm formation and screening biofilm inhibitors will have great value in reducing bacterial drug-resistance, which is beneficial to prevent and treat biofilmassociated infections. In…

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