Abstract:SummaryThis work identified a cycle of actin assembly and disassembly in large secretory vesicles of Drosophila salivary glands. Actin disassembly is triggered by actindependent recruitment of a RhoGAP protein, and is essential for the contractility of the vesicle leading to content release to the lumen.
AbstractSecretion of adhesive glycoproteins to the lumen of Drosophila larval salivary glands is carried out by contraction of an actomyosin network that is assembled around large secretory vesicles, following… Show more
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