Formate for enhancing the growth of microalgae and accumulating high-value products

Jiang, Jing; Li, Xinwei; Yang, Kaiguang; Wang, Yan; Ye, Mingliang; Wang, Wangyin; Cao, Xupeng; Li, Can

doi:10.1016/j.algal.2023.103261

Cited by 7 publications

(3 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[162][163][164] Formate inhibits its activity, and Carbonic anhydrase was the only protein that was significantly increased in the format-containing conditions in the selected strain. [161,162] Therefore, as a high rate of CO 2 fixation is closely linked to the growth of microalgae, efforts are being made to improve CO 2 fixation in combination with the oxidative stress response to promote the production of lipids and carotenoids. Applications of culturing methods and gene editing technology towards enhancement of CO 2 fixation are presented in Table 3.…”

Section: Chlamydomonas Reinhardtiimentioning

confidence: 99%

“…[ 162–164 ] Formate inhibits its activity, and Carbonic anhydrase was the only protein that was significantly increased in the format‐containing conditions in the selected strain. [ 161,162 ]…”

Section: Co2 Supplementation or Genetic Modifications Of Co2 Fixation...mentioning

confidence: 99%

“…[160] Accordingly, the expression level of carbonic anhydrase was increased by selecting a strain capable of growing in the media containing up to 60 mM of formate as a carbon source, leading to higher protein content but lower biomass accumulation. [161] Carbonic anhydrase is involved in the inorganic carbon concentration, especially in low carbon conditions. [162][163][164] Formate inhibits its activity, and Carbonic anhydrase was the only protein that was significantly increased in the format-containing conditions in the selected strain.…”

Section: Chlamydomonas Reinhardtiimentioning

confidence: 99%

See 2 more Smart Citations

Recent advances and fundamentals of microalgae cultivation technology

Rozenberg,

Sorokin,

Mukhambetova

et al. 2024

Biotechnology Journal

View full text Add to dashboard Cite

Microalgae are considered to be a promising group of organisms for fuel production, waste processing, pharmaceutical applications, and as a source of food components. Unicellular algae are worth being considered because of their capacity to produce comparatively large amounts of lipids, proteins, and vitamins while requiring little room for growth. They can also grow on waste and fix CO2 and nitrogen compounds. However, production costs limit the industrial use of microalgae to the most profitable applications including micronutrient production and fish farming. Therefore, novel microalgae based technologies require an increase of the production efficiencies or values. Here we review the recent studies focused on getting strains with novel characteristics or cultivating techniques that improve production's robustness or efficiency and categorize these findings according to the fundamental factors that determine microalgae growth. Improvements of light and nutrient delivery, as well as other aspects of photobioreactor design, have shown the highest average increase in productivity. Other methods, such as an improvement of phosphorus or CO2 fixation and temperature adaptation have been found to be less effective. Furthermore, interactions with particular bacteria may promote the growth of microalgae, although bacterial and grazer contaminations must be managed to avoid culture failure. The competitiveness of the algal products will increase if these discoveries are applied to industrial settings.

show abstract