Formate Dehydrogenase: Recent Developments for NADH and NADPH Recycling in Biocatalysis
Artur Maier,
Lindelo M. Mguni,
Anna C. R. Ngo
et al.
Abstract:Formate dehydrogenases (FDHs) catalyze the oxidation of formate to CO2 while reducing NAD(P)+ to NAD(P)H and are classified into two main classes: metal‐dependent (Mo‐ or W‐containing) and metal‐independent FDHs. The latter are oxygen‐tolerant and relevant as a cofactor regeneration system for various bioprocesses and gained more and more attention due to their ability to catalyze the reverse CO2 reduction. This review gives an overview of metal‐independent FDHs, the recent advances made in this field, and the… Show more
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