“…In addition to past tendencies to implement one-by-one interventions rather than a group of interlaced programmes that constitute a mosaic of actions,8 there are inherent barriers to effective prevention,9 especially as programmes have focused on seeking to detect persons at high risk as they enter perisuicidal periods and approach the precipice of death. These include: an inability to discriminate the relatively few true cases from the large number of false positive cases, that is, the preponderance of persons suffering severe psychological distress with diagnosed psychiatric disorders who, even while suicidal, neither attempt nor die by suicide; the large number of false-negative cases that escape preventive detection, that is, persons who seemed ‘normal’ but killed themselves or whose long-standing condition appeared no worse to family, friends or providers during the days immediately before their death; the inability of clinical and social services to reach many individuals who have serious suicidal intent; a continuing paucity of knowledge about fundamental biological, psychological, social and cultural factors that contribute to fatal suicide attempts among diverse populations and groups who have been labelled at-risk; and the lack of coordinated strategies for suicide prevention that can deal effectively with myriad local, regional, state and national agencies and organisations that could, in theory, play a role in preventing suicide.…”