Forensic Science

Brettell, Thomas A.; Saferstein, Richard

doi:10.1021/a1970005c

Cited by 12 publications

(5 citation statements)

References 703 publications

(655 reference statements)

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“…The analysis of exhaled breath has received considerable attention [1][2][3][4][5] and is an interesting alternative to blood sampling: provided that a suitable apparatus is available, it does not require specialized personnel or generate hazardous waste. Although its chemical composition is chemically diverse, breath is still a simpler matrix than plasma.…”

mentioning

confidence: 99%

“…In spite of these advantages only a few techniques based on breath sampling have found a niche in clinical or forensic analysis, e.g., to diagnose H. pylori infection 3 or the degree of alcohol intoxication. 4 Difficulties encountered in breath analysis include lack of simple or suitable separation, identification, quantitation, and standardization techniques 5 ; tedious sample collection and pre-treatment protocols are necessary for some techniques, e.g. exhaled breath condensate analysis.…”

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confidence: 99%

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Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath

et al. 2011

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confidence: 99%

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Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath

et al. 2011

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“…Tom Brettell and Rich Saferstein began these reviews while working at the New Jersey State Police Forensic Science Bureau (Hamilton, NJ) and the first eight reviews (1983–1997) were written solely by them [ 46 – 53 ]. Additional co-authors were included in more recent reviews to gain further expertise on specific forensic disciplines.…”

Section: Progress Report and Thoughts On The Futurementioning

confidence: 99%

U.S. initiatives to strengthen forensic science & international standards in forensic DNA

Butler

2015

Forensic Science International: Genetics

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A number of initiatives are underway in the United States in response to the 2009 critique of forensic science by a National Academy of Sciences committee. This article provides a broad review of activities including efforts of the White House National Science and Technology Council Subcommittee on Forensic Science and a partnership between the Department of Justice (DOJ) and the National Institute of Standards and Technology (NIST) to create the National Commission on Forensic Science and the Organization of Scientific Area Committees. These initiatives are seeking to improve policies and practices of forensic science. Efforts to fund research activities and aid technology transition and training in forensic science are also covered. The second portion of the article reviews standards in place or in development around the world for forensic DNA. Documentary standards are used to help define written procedures to perform testing. Physical standards serve as reference materials for calibration and traceability purposes when testing is performed. Both documentary and physical standards enable reliable data comparison, and standard data formats and common markers or testing regions are crucial for effective data sharing. Core DNA markers provide a common framework and currency for constructing DNA databases with compatible data. Recent developments in expanding core DNA markers in Europe and the United States are discussed.

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“…Numerous methods for the quantification of cocaine and its metabolites have been reviewed. 4,5 Although chromatographic methods dominate the list of procedures reported, [6][7][8][9][10][11][12][13][14][15][16][17][18] other methods of determination include voltametry, 19 amperometry, 20 potentiometry, 21 and calorimetry. 22 Analytical procedures based on the principles of ion-pair formation between the protonated alkaloid and a negatively charged metal-containing species have been developed for the indirect AAS determination of alkaloids [23][24][25][26] and chemiluminescence determination of atropine.…”

Section: Introductionmentioning

confidence: 99%

Indirect Atomic Absorption Determination of Cocaine via Formation and Liquid‐liquid Extraction of the Iron(III)‐cocaine Complex

Mohammadzai

Hinze

2004

J Chinese Chemical Soc

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The principles of metal-alkaloid ion-pair formation and liquid-liquid extraction are applied to the development of a sensitive and convenient atomic absorption spectrophotometery (AAS) method for the indirect determination of cocaine. In an aqueous medium of 5 M hydrochloric acid, cocaine is protonated and is associated with tetrachloro ferrate (III) anion prior to its extraction into 1,2-dichloroethane. The critical experimental variables were identified and optimized. The method is simple and reproducible with a detection limit (DL) of 0.1 ng cm -3 cocaine in water, a relative standard deviation of 0.07 (n = 12), and the calibration graph was linear up to 50 ng cm -3 cocaine.

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Forensic Science

Cited by 12 publications

References 703 publications

Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath

Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath

U.S. initiatives to strengthen forensic science & international standards in forensic DNA

Indirect Atomic Absorption Determination of Cocaine via Formation and Liquid‐liquid Extraction of the Iron(III)‐cocaine Complex

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