Abstract:In the present study, a generic dosage form of metformin hydrochloride was developed using deformulation of a marketed product. The excipients used in the marketed product were identified using thermospectral method such as differential scanning calorimetry (DSC). The marketed formulation contained metformin hydrochloride 850 mg. The ingredients present in the marketed dosage form after performing thermal analysis were identified as metformin hydrochloride, sodium carboxymethyl cellulose, microcrystalline cell… Show more
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