Foreign- vs US-born Asians and the association of type I uterine cancer

Simons, Elise J.; Blansit, Kevin; Tsuei, Torie; Brooks, Rebecca; Ueda, Stefanie; Kapp, Daniel S.; Chan, John K.

doi:10.1016/j.ajog.2014.07.019

Cited by 11 publications

(6 citation statements)

References 33 publications

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“…The prevalence of overweight and obesity is increasing worldwide, but the rates vary by country 25,26 . This variation suggested that different risk profiles and protective factors might be found in different countries 27 . The Nutrition and Health survey conducted in Taiwan (NAHSIT) showed that the location of residence, educational level, and physical activity were correlated with obesity 11 .…”

Section: Discussionmentioning

confidence: 98%

Age-specific trend and birth cohort effect on different histologic types of uterine corpus cancers

Tai

Chiang

et al. 2023

Sci Rep

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To evaluate the uterine corpus cancer incidence rates, age-specific trends, and birth cohort patterns by different histologic types. We conducted a retrospective cohort study of uterine cancer patients (n = 28,769) of all ages from the National Cancer Registry of Taiwan between 1998 and 2017. We estimated the incidence trends, average annual percent changes (AAPCs), and cancer-specific survival (CSS) rate for the two main subtypes (endometrioid and nonendometrioid) of uterine cancer in Taiwan. During the study period, uterine corpus cancer incidence rates increased over time from 5.3 to 15.21 per 100,000 women. Incidence trends for endometrioid carcinoma increased in all age groups (positive AAPCs > 5% for each age group), and the rise was steeper among women aged 50 years and younger. For nonendometrioid carcinomas, incidence rates increased among women over 50 years. The CSS rate improved among women with stage I (hazard ratio [HR] 0.63, 95% confidence interval [CI] 0.49–0.81) and stage III (HR 0.72, 95% CI 0.58–0.90) endometrioid carcinomas after 2013 compared with those during 2009–2012. However, the CSS rate remained unchanged for nonendometrioid carcinomas. Age, diagnostic period, stage and histologic types were significant factors associated with the 5-year CSS rate. We found that the incidences of both endometrioid and nonendometrioid carcinomas continued to increase among contemporary birth cohorts. Etiologic research is needed to explain the causes of these trends.

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Section: Discussionmentioning

confidence: 98%

Age-specific trend and birth cohort effect on different histologic types of uterine corpus cancers

Tai

Chiang

et al. 2023

Sci Rep

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“…The prevalence of overweight status and obesity are increasing globally, but the rates vary by country [23,24]. This variation suggested that different risk pro les and protection factors might be found in different countries [25]. The Nutrition and Health survey conducted in Taiwan (NAHSIT) showed that the location of residence, educational level, and physical activity were correlated with obesity [11].…”

Section: Discussionmentioning

confidence: 99%

Age-Specific Trend and Birth Cohort Effect on Different Histologic Types of Uterine Corpus Cancers

Tai

Chiang²,

Chiang

et al. 2021

Preprint

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To evaluate the uterine corpus cancer incidence rates, age-specific trends and birth cohort patterns by different histologic types. From the Taiwan Cancer Registry, we identified women with a primary diagnosis of uterine corpus cancer (n=28 769) from1998 to 2017. We analyzed the incidences, stages of disease at diagnosis and prognostic factors in endometrioid and non-endometrioid carcinoma. During the study period, uterine corpus cancer incidence rates increased over time from 5.3 to 15.21 per 100 000 woman-years. Incidence trends for endometrioid carcinoma increased in all age groups and the rise was steeper in women age 40 years and younger. For non-endometrioid carcinomas, incidence rates increased in women over 50 years. Women diagnosed after 2013 had significantly better cancer-specific survival (CSS) (hazard ratio [HR] =0.81, 95% confidence interval [CI] 0.73-0.89) compared with those at the period of 2009-2012. CSS also improved in stage I (HR=0.81, 95% CI 0.49-0.63) and stage III (HR 0.90, 95% CI 0.58-0.72) endometrioid carcinomas after 2013. Whereas CSS remained unchanged for non-endometrioid carcinomas. We found the incidences of both endometrioid and non-endometrioid carcinomas continued to increase among contemporary birth cohorts. Etiologic research is mandatory to explain the causes for these trends.

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“…We found a wide range of ages among the subpopulations, from age 55 in Vietnamese to 72 in Japanese, which suggests potential discrepancies in risk factors for each of the Asian subpopulations. Factors such as immigration status have been shown to be associated with uterine cancer age of diagnosis and histologic subtype, and each Asian subpopulation experiences different rates of immigration [ 14 20 ]. Foreign-born Asians have been found to be younger at diagnosis compared with those born in the US [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Notably, data extracted from the 2015 US Census Bureau shows that 64% of the Vietnamese in the US are foreign-born compared with only 27% of the Japanese, which may help explain discrepancies between age of diagnosis for these subpopulations [ 21 ]. Furthermore, Simons et al [ 14 ] reported that Asian immigrants have higher proportions of type II uterine cancer, which includes UCCC, endometrioid grade 3 carcinoma, and serous carcinoma, compared with US-born Asians. Type II uterine cancer was found to be highest in immigrants who were Japanese, followed by Chinese and Filipino.…”

Section: Discussionmentioning

confidence: 99%

“…The risk of UCCC in other racial minorities has not been as thoroughly studied as that in Blacks. Given the low rate of UCCC and small sample sizes of minority populations, prior studies on UCCC in Asians have pooled UCCC with other aggressive uterine histologic subtypes, such as serous carcinoma [ 13 14 ]. Asians have been shown to be diagnosed at younger ages and have higher proportions of aggressive histologic subtypes (including UCCC) compared with white women [ 13 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Uterine clear cell carcinoma risk in White versus non-White US subpopulations: does race matter?

et al. 2020

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Objective To determine incidence rates of uterine clear cell carcinoma among non-White US subpopulations. Methods Data from the United States Cancer Statistics and National Cancer Database from 2004 to 2016 were analyzed using descriptive statistics. Results A total of 488,811 women were diagnosed with uterine cancer from 2004–2016. Of these, 73.3% were endometrioid, 6.6% were serous, 5.3% were carcinosarcoma, 1.4% were clear cell, and 13.4% were other. Blacks had the highest incidence rate of uterine clear cell compared with Whites, Asian/Pacific Islanders, and American Indian/Alaska Natives (0.59 vs. 0.31, 0.29, and 0.24, respectively). Overall mean age at diagnosis was 68.6 years, with the youngest age in Asian/Pacific Islanders compared to Whites, Blacks, and American Indian/Alaska Natives (65.9 vs. 68.7, 68.6, and 66.3 years, respectively). Analysis of the Asian subpopulation revealed significantly younger age at diagnosis in Vietnamese women (55.8 years) compared with 72.4 years in Japanese, 68.6 years in Pacific Islander, 66.6 years in Indian/Pakistani, 65.9 years in Filipino, 65.8 years in Chinese, 65.2 years in Korean, and 63.7 years in other Asians. Conclusions Black women are two times more likely to be diagnosed with uterine clear cell carcinoma compared with other races. Asians present at younger ages, with Vietnamese women most likely to be diagnosed at the youngest age.

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Foreign- vs US-born Asians and the association of type I uterine cancer

Cited by 11 publications

References 33 publications

Age-specific trend and birth cohort effect on different histologic types of uterine corpus cancers

Age-specific trend and birth cohort effect on different histologic types of uterine corpus cancers

Age-Specific Trend and Birth Cohort Effect on Different Histologic Types of Uterine Corpus Cancers

Uterine clear cell carcinoma risk in White versus non-White US subpopulations: does race matter?

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