Foreign Body Granulomata of the Lungs Due to Liquid Paraffin

Wagner, J. C.; Adler, D. I.; Fuller, D. N.

doi:10.1136/thx.10.2.157

Cited by 35 publications

(12 citation statements)

References 9 publications

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“…Aspirated oils produce essentially the same response to injury, differing only in the rapidity and severity of the elicited response and producing an interstitial proliferative granulomatous pneumonia. 8 Wagner et al 8 described the development of lipoid pneumonia and divided it into four stages based on the evolution of the histological abnormalities. Stage 1 is characterized by a hemorrhagic consolidative pneumonia, especially when animal oils are aspirated.…”

Section: Discussionmentioning

confidence: 99%

Infantile Lipoid Pneumonia

et al. 1990

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Section: Discussionmentioning

confidence: 99%

Infantile Lipoid Pneumonia

et al. 1990

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“…Most other oily substances stain scarlet with Sudan IV and black with osmic acid. Vicks Salve or Vapo-Rub and most oily nosedrops contain a mixture of oils, including mineral oil or petroleum jelly, eucalyptus oil, and cedar leaf oil, among others [5,21]. According to Sante [2], mineral oil cannot be saponified and therefore is not digested by phagocytes, so that the oil droplets often persist and incite tissue reaction.…”

Section: Commentmentioning

confidence: 99%

Carcinoma of the lung complicating lipoid pneumonia

Felson¹,

Ralaisomay²

1983

American Journal of Roentgenology

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We have encountered four patients in whom a localized area of exogenous lipoid pneumonia appeared to undergo malignant degeneration. These four patients, two of whom were from the University of Cincinnati Medical Center and two from other institutions, plus six similar patients culled from the literature, form the basis of this report.In each case, the malignant process occurred in the same location in the lung as the lipoid granuloma. In no instance was the malignant change recognized in its early phase, but in several cases in which the diagnosis of lipoid pneumonia had been established, accelerated spread of the lesion eventually led to the recognition of the superimposed carcinoma.

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“…To distinguish between mineral oils on the one hand, and vegetable and animal oils on the other, use has been made of the reaction of osmium tetroxide, which is reduced by the animal and vegetable oils to give a black precipitate, whilst mineral oils have no such action. Some investigators have carried out chemical analysis of lung tissue (Jampolis et al, 1953;Wagner et al, 1955). CaEistories Case 1.-A woman aged 54 was admitted to hospital on January 17, 1956, with a diagnosis of bronchitis, bronchiectasis, and right-sided heart failure.…”

Section: Liquid Paraffin Asmentioning

confidence: 99%