During a diagnostic esophagogastroduodenoscopy (EGD) and colonoscopy, a foreign material was found coating a patient’s stomach and proximal colon. Polypectomy with a hot snare and cold forceps proved unsuccessful, as the endoscope channels clogged. Thereafter, the patient confessed to taking one bottle of Tums (GlaxoSmithKline, St. Louis, Missouri, US) daily for an unknown duration. The medication was discontinued and a repeat colonoscopy showed complete resolution. The costs of repeat procedures, reduced efficacy, as well as equipment damage or refurbishment are substantial, and so providers should note that this may be the result of excessive calcium carbonate (similarly to barium) and instruct the patients to adjust intake accordingly.