Force spectroscopy measurements of MoSIx nanowires with functionalized molecules

Abstract

We report a simple method of functionalization of MoSIx nanowires with biomaterials via the thiol group. We succeed to immobilize iodinated and sulphated high molecular mass thyroglobulin proteins on MoSIx nanowires. By controlling the preparation of the nanowires before self-assembly we can attach proteins either at the ends or achieve complete wrapping of the nanowires. The control parameter is the S and I stoichiometry ratio of the MoSIx nanowires. Breaking force measurements were performed in order to confirm and characterise the wrapping of the nanowires with the proteins.

Compositional ordering and quantum transport inMo6S9−xIxnanowires:Ab initiocalculations

“…Combining subnanometer diameter with structural stability and interesting electronic properties, transition metal chalcogenide nanowires have been discussed as a potentially viable alternative to carbon nanotubes 1 for many applications. In particular, Mo 6 S 9−x I x nanowires have been extensively studied both experimentally [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] and theoretically. [19][20][21] In contrast to other nanowires and nanotubes, Mo 6 S 9−x I x are believed to be metallic independent of their structure 3,19,20 and can be synthesized, 22 dispersed, 5,6 and functionalized 7 in a straightforward manner.…”

Mo6S9-xIx Nanowire Recognitive Molecular-Scale Connectivity

“…In sensors and in larger circuits, it may be useful to electrically insulate the leads. Immobilization of nonconducting proteins on the surface of MoSIx nanowire bundles, such as has been recently demonstrated, may be used for this purpose, leaving electrical contact only at the functionalized ends. In many nanoelectrode applications it is important that the connector has mechanical stability, for which thicker MW bundles can be chosen.…”