For Someone, You Are the Whole World: Host-Specificity of Salmonella enterica
Anastasiya V. Merkushova,
Anton E. Shikov,
Anton A. Nizhnikov
et al.
Abstract:Salmonella enterica is a bacterial pathogen known to cause gastrointestinal infections in diverse hosts, including humans and animals. Despite extensive knowledge of virulence mechanisms, understanding the factors driving host specificity remains limited. In this study, we performed a comprehensive pangenome-wide analysis of S. enterica to identify potential loci determining preference towards certain hosts. We used a dataset of high-quality genome assemblies grouped into 300 reference clusters with a special … Show more
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