Foot and ankle tuberculosis: Case series and literature review

Korim, M.T.; Patel, Rizwan; Allen, Patricia; Mangwani, Jitendra

doi:10.1016/j.foot.2014.07.006

Cited by 20 publications

(26 citation statements)

References 11 publications

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“…The bones and joints are affected in just 1% to 3% of all cases of TB, and the spine and the hip are most common sites involved when bone is infected. The foot accounts for only about 10% of all cases of tuberculous osteomyelitis [1]. In the present report, we describe a case of tuberculous osteomyelitis localized to the first metatarsophalangeal (MTP) joint misdiagnosed as gouty arthritis in a 43 year old man.…”

Section: Introductionmentioning

confidence: 85%

“…Tuberculous osteomyelitis constitutes 1% to 3% of extrapulmonary cases and most commonly affected sites are spine, femur, tibia, and fibula [1]. The ankle and foot are rarely affected and account for only 1% of all TB infections.…”

Section: Discussionmentioning

confidence: 99%

“…Because of its indolent nature and lack of specific symptoms, skeletal TB may underrecognized for months to years. The average duration from first symptom to diagnosis varies depending on reports, it was between 11 to 26 months in most studies [1]. The rarity of the problem and a low index of suspicion often lead to delayed diagnosis and potentially worse outcomes.…”

Section: Discussionmentioning

confidence: 99%

“…The radiologic features of tuberculous osteomyelitis are nonspecific. The plain radiography is necessary for detecting bone destruction, but radiographic features are noted 2 to 5 months after symptom on-set, only a joint effusion is early sign in most cases [1]. MRI is accepted as most useful imaging modality in aiding diagnosis and revealing the extent of the disease.…”

Section: Discussionmentioning

confidence: 99%

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Tuberculous Osteomyelitis of the First Metatarsophalangeal Joint Misdiagnosed as Gouty Arthritis

et al. 2016

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A-43-year-old man visited our clinic due to pain and swelling of his left first metatarsophalangeal (MTP) joint since 6-months ago. He was diagnosed as gouty arthritis at private clinic and took hypouricemic agent, but he had progressive pain and swelling. There was swelling, erythema and tenderness and ulceration at base of the left first MTP joint. His laboratory results showed elevated C-reactive protein and normal serum uric acid level. The plain radiograph of foot showed bone destruction of left first MTP joint. MRI revealed joint space narrowing, soft tissue swelling and subchondral cyst. He underwent excisional biopsy and histology demonstrated chronic granulomatous inflammation with caseation necrosis. Tissue polymerase chain reaction for mycobacterium tuberculosis was positive. He was diagnosed as tuberculous osteomyelitis. He started on quadruple anti-tuberculous therapy and his symptom was improved. Early diagnosis and anti-tuberculosis therapy could lead to improve outcomes. (J Rheum Dis 2016;23:311-315)

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Section: Introductionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Tuberculous Osteomyelitis of the First Metatarsophalangeal Joint Misdiagnosed as Gouty Arthritis

et al. 2016

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“…Typically, the lytic areas of destruction and erosions are seen along the articular margins. In the initial stages of the disease, there is relative preservation of the joint space, differently from septic arthritis, while at more advanced stages joint destruction, sclerosis and fibrous ankylosis are present [5] . An MRI examination can be useful especially to more precisely define bone and soft tissue involvement.…”

Section: Discussionmentioning

confidence: 99%

Tuberculous Arthritis of the Ankle

Rando

Matteis

Gessi

et al. 2018

European Journal of Case Reports in Internal Medicine

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Tuberculosis (TB) is an infectious disease caused by the Mycobacterium tuberculosis complex (MTBC). Pulmonary TB is the most common form of presentation, but extrapulmonary tuberculosis (EPTB) contributes significantly to morbidity and mortality. Rarely, patients with EPTB develop a form of ankle or foot arthritis. The diagnosis of TB arthritis is often overlooked because of the insidious onset and the non-specific clinical symptoms. Prognosis is generally poor; early diagnosis and delivery of the most appropriate treatment is critical to avoid functional disability.LEARNING POINTSTuberculous arthritis of the ankle has high morbidity but often goes undiagnosed.Tuberculous arthritis of the ankle can lead to degenerative changes in the bone and articular cartilage and even to joint collapse.Timely diagnosis and correct treatment are important to avoid functional disability.

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