Foodborne trematodes

Waikagul, Jitra; Sato, Megumi

doi:10.1016/b978-1-78242-332-4.00010-2

Cited by 3 publications

(2 citation statements)

References 109 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…O . viverrini is a fishborne fluke and, like Taenia and its infection to humans is related to the consumption of raw fish meat (cyprinid fish) [ 37 ] and to domestic dogs, natural reservoirs of O . viverrini , which can be an important source of aquatic environment contamination because of its routine behavior to assess water sources [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

Taenia solium, Taenia saginata, Taenia asiatica, their hybrids and other helminthic infections occurring in a neglected tropical diseases' highly endemic area in Lao PDR

Sato

Yanagida

et al. 2018

PLoS Negl Trop Dis

View full text Add to dashboard Cite

Most part of Southeast Asia is considered endemic for human-infecting Taenia tapeworms; Taenia solium, T. saginata, and T. asiatica. However, until now there was no report of the occurrence of human cases of T. asiatica in Lao PDR. This study, conducted in Savannakhet Province, Lao PDR, microscopically examined a total of 470 fecal samples by Kato Katz method and found 86% of people harboring at least one helminth. Hookworms were detected in 56% of the samples besides Opisthorchis like eggs (42%), Trichuris trichiura (27%), Ascaris spp. (14%), and Taenia spp. (4%) eggs. Serology for cysticercosis showed 6.8% positives with results varying from 3% to 14.3% in Ethnic School students and Kalouk Kao village respectively. Species-specific PCR targeting mitochondrial DNA (mtDNA) of 28 tapeworms, recovered from 16 patients, revealed T. solium (n = 2), T. saginata (n = 21), and T. asiatica (n = 5). Two patients were confirmed to be coinfected with T. saginata and T. asiatica, indicating the endemicity of the 3 human Taenia in Lao PDR. However, nucleotide sequencing of a nuclear DNA gene, DNA polymerase delta (pold) revealed that all the tapeworms identified as T. asiatica using mtDNA had T. saginata type allele at pold locus, demonstrating that they are not “pure T. asiatica” but the hybrid descendants between the two species, confirming the wide distribution of hybrids of T. saginata/ T. asiatica in Southeast Asia. The high prevalence of several helminthic NTDs in east Savannakhet area even with conventional control measures indicates the importance to establish wide and multifaceted health programs to sustainably improve the quality of life of the populations living in these communities.

show abstract

Section: Discussionmentioning

confidence: 99%

Taenia solium, Taenia saginata, Taenia asiatica, their hybrids and other helminthic infections occurring in a neglected tropical diseases' highly endemic area in Lao PDR

Sato

Yanagida

et al. 2018

PLoS Negl Trop Dis

View full text Add to dashboard Cite

show abstract

“…Fascioliasis is a parasitic disease caused by liver fluke species of the genus Fasciola (Digenea: Fasciolidae) and considered as one of the most important helminthic diseases. The giant hepatic flukes, F. gigantica and F. hepatica are plant-borne trematodes, leaf-shaped flatworms, which were diagnosed in the liver of some economical livestock such as cattle, sheep, buffaloes, goats, swine, and other domestic animals while the world health organization (WHO) had reported their significant impact on the human being, as well [1]. Both species had significant impacts on the growth rate, development, and productivity of ruminants, therefore, they are considered economically substantial [2].…”

Section: Introductionmentioning

confidence: 99%

Fasciola Gigantica: Tegumental Surface Alterations Following Treatment in Vitro with Plumbagin

2021

Al-Azhar University Journal of Virus Researches and Studies

View full text Add to dashboard Cite

Fascioliasis is a parasitic disease caused by liver fluke species of the genus Fasciola. Triclabendazole is the only known treatment to be efficient against both the pre-adults and adults' worms in hepatic parenchyma and the bile ducts, respectively, however, its effectiveness was found to be confronted by some resistance issues. This work aimed to investigate the antiparasitic effect of Plumbagin (PB) against the adult Fasciola gigantica (F. gigantica) parasite. PB is natural yellowish quinonoid compound, 5-hydroxy-2-methyl-1,4naphthoquinone, which is known to have an antiparasitic and anthelmintic activity in both humans and animals. In the current study, the anthelmintic efficacy of PB was assessed by using 40 flukes of the adult F. gigantica which were divided into four groups (10 each). Three groups were treated with different concentrations of PB (1, 10, and 100 μg/ml) and the fourth group was left untreated to act as a negative control. The efficacy of PB against F. gigantica was assessed by scanning electron microscopic (SEM) and histopathological examination of the tegument area in the posterior part of the fluke's body. The results showed that PB caused tegumental alterations, including swelling, blebbing, and rupture of the tegument, loss of spines, eventual erosion, and even desquamation of the total tegument, in a dose dependentmanner. The severity of tegumental damage increased, proportionally, with the concentrations of PB to indicate its fasciolicidal effect against adult F. gigantica. Further studies are recommended for its potential use as an anthelmintic against Fasciola sp. infections.

show abstract