Foodborne botulism in southwest Romania during the post-communism period 1990–2007

Neghină, Adriana Maria; Marincu, Iosif; Moldovan, Roxana; Iacobiciu, Ioan

doi:10.1016/j.ijid.2009.03.022

Cited by 11 publications

(17 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Its hardy spores are ubiquitously spread in soil and aquatic sediments and commonly contaminate foods [2,6]. Spores are heat-resistant and survive in standard cooking practices that do not exceed 100 °C [7]. Bacterial growth is inhibited by refrigeration below 4 °C, heating above 121 °C, acidity (pH <4.5) or high water activity [2].…”

Section: Introductionmentioning

confidence: 99%

“…The toxin interferes with presynaptic release of acetylcholine in the parasympathetic and the sympathetic systems as well as the neuromuscular junctions [1,7,10,15]. A clinical pattern of acute symmetrical descending flaccid paralysis is characteristic for botulism.…”

Section: Introductionmentioning

confidence: 99%

“…A clinical pattern of acute symmetrical descending flaccid paralysis is characteristic for botulism. Other common presentations include abdominal pain, vomiting, constipation, blurred vision, and diplopia [1,7,10,11,14,16].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Foodborne Botulism: A Study of 57 Cases in Northwest Iran

Nejadrahim

Delirrad

2016

IJT

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Foodborne Botulism: A Study of 57 Cases in Northwest Iran

Nejadrahim

Delirrad

2016

IJT

View full text Add to dashboard Cite

show abstract

“…Despite the fact that the incidence of botulism cases was among the highest in the western region of Romania during 2007-2009 (0.3 cases per 100,000 inhabitants), this value is four times lower than the figure reported in the same area during 1990-2007 (1.4 cases per 100,000 inhabitants) (Neghina et al, 2010), demonstrating an improvement in the public awareness of the conditions that have led to foodborne botulism in this region of Romania.…”

mentioning

confidence: 58%

Epidemiology of Foodborne Botulism in Romania 1980–2009

Neghină

2011

Foodborne Pathogens and Disease

Self Cite

View full text Add to dashboard Cite

In 2007, Romania, the largest southeastern European country, reported the highest notification rate of botulism cases in the European Union (0.18 per 100,000 inhabitants), which was 18 times higher than the reported rate in the United States (0.01 per 100,000 inhabitants). This report aims to analyze published and unpublished surveillance data on foodborne botulism in Romania from 1980 to 2009 in the context of political and economical changes that occurred in the former communist countries. The mean annual incidence rate of botulism cases was significantly lower during the late communist period, 1980-1989 (0.06±0.03 cases per 100,000 inhabitants), than during the years 1990-1999 (0.1±0.04 cases per 100,000 inhabitants, p=0.01) and 2000-2009 (0.12±0.04 cases per 100,000 inhabitants, p<0.01). The highest incidence rates were registered in 1998 and 2007 (0.18 cases per 100,000 inhabitants), whereas the lowest incidence rate was registered in 1983 (0.02 cases per 100,000 inhabitants). The disease was usually associated with the consumption of home prepared meat products (mainly raw sausages, smoked-dried meat). Most of the laboratory-confirmed cases tested positive for type B toxin (99%). During 2007-2009, the incidence was particularly high in northwestern and western Romania (0.5 and 0.3 cases per 100,000 inhabitants, respectively). The fatality rate was 60% before 1995 and decreased to 12.2±8.5% during 1999-2009. The general ascending trend of infection rates throughout the period studied demonstrates the need for the implementation of correct public health and educational measures to fully prevent this severe disease.

show abstract

“…In Europe, foodbome botulism cases are often associated with meat products and are caused by group II (nonproteo lytic) C. botulinum type B (75, 22,26,27,31). Group II C. botulinum strains are psychrotrophic and thus able to grow at refrigerated temperatures.…”

mentioning

confidence: 99%

Inhibition of Toxigenesis of Group II (Nonproteolytic) Clostridium botulinum Type B in Meat Products by Using a Reduced Level of Nitrite

Keto-Timonen

Lindström

Puolanne

et al. 2012

Journal of Food Protection

View full text Add to dashboard Cite

The effect of three different concentrations of sodium nitrite (0, 75, and 120 mg/kg) on growth and toxigenesis of group II (nonproteolytic) Clostridium botulinum type B was studied in Finnish wiener-type sausage, bologna-type sausage, and cooked ham. A low level of inoculum (2.0 log CFU/g) was used for wiener-type sausage and bologna-type sausage, and both low (2.0 log CFU/g) and high (4.0 log CFU/g) levels were used for cooked ham. The products were formulated and processed under simulated commercial conditions and stored at 8°C for 5 weeks. C. botulinum counts were determined in five replicate samples of each nitrite concentration at 1, 3, and 5 weeks after thermal processing. All samples were positive for C. botulinum type B. The highest C. botulinum counts were detected in nitrite-free products. Toxigenesis was observed in nitrite-free products during storage, but products containing either 75 or 120 mg/kg nitrite remained nontoxic during the 5-week study period, suggesting that spores surviving the heat treatment were unable to germinate and develop into a toxic culture in the presence of nitrite. The results suggest that the safety of processed meat products with respect to group II C. botulinum type B can be maintained even with a reduced concentration (75 mg/kg) of sodium nitrite.

show abstract

Foodborne botulism in southwest Romania during the post-communism period 1990–2007

Abstract: Although the botulism cases decreased over the study period in southwest Romania, this life-threatening disease continues to be an important concern. A strategy addressing individual behaviors in the home is needed to improve food safety.

Cited by 11 publications

References 15 publications

Foodborne Botulism: A Study of 57 Cases in Northwest Iran

Foodborne Botulism: A Study of 57 Cases in Northwest Iran

Epidemiology of Foodborne Botulism in Romania 1980–2009

Inhibition of Toxigenesis of Group II (Nonproteolytic) Clostridium botulinum Type B in Meat Products by Using a Reduced Level of Nitrite

Contact Info

Product

Resources

About