Food Reservoir forEscherichia coliCausing Urinary Tract Infections

Abstract

Closely related strains of Escherichia coli have been shown to cause extraintestinal infections in unrelated persons. This study tests whether a food reservoir may exist for these E. coli. Isolates from 3 sources over the same time period (2005–2007) and geographic area were compared. The sources comprised prospectively collected E. coli isolates from women with urinary tract infection (UTI) (n = 353); retail meat (n = 417); and restaurant/ready-to-eat foods (n = 74). E. coli were evaluated for antimicrobial drug susceptibility and O:H serotype and compared by using 4 different genotyping methods. We identified 17 clonal groups that contained E. coli isolates (n = 72) from >1 source. E. coli from retail chicken (O25:H4-ST131 and O114:H4-ST117) and honeydew melon (O2:H7-ST95) were indistinguishable from or closely related to E. coli from human UTIs. This study provides strong support for the role of food reservoirs or foodborne transmission in the dissemination of E. coli causing common community-acquired UTIs.

First detection of extended-spectrum cephalosporin- and fluoroquinolone-resistant Escherichia coli in Australian food-producing animals

“…and Europe, but also as a sporadic cause of human extraintestinal infections in Canada, Chile, France, Spain and Brazil [23,24] (http://mlst.warwick.ac.uk/mlst/dbs/Ecoli). ST10 is an extremely diverse and broadhost-range lineage causing extraintestinal infections in hospitalised and communitydwelling humans in The Netherlands and Canada [24][25][26], and is also detected in poultry, wild birds and pigs as well as retail chicken and pork meat [24][25][26][27].…”

Antibacterial Activity of Methanolic Extract of Mangifera Indica (Bark) and Osyris Lanceolata (Leaves) From Western Region of Nepal

“…[10] Uncomplicated urinary tract infections caused by E. coli cause serious illness and death. [11] Antibiotics used in the study Ampicillin: Ampicillin is a β-lactam antibiotic which belongs to semisynthetic penicillin. It inhibits bacterial growth by interfering with the transpeptidation reaction of bacterial cell wall synthesis.…”

The globalization of intestinal microbiota

“…It should be noted that this globalization of food has been involved in a series of pandemics, such as epidemics of Escherichia coli contamination in chicken products causing urinary infections in humans [12]. Indeed, epidemics that occur in the farm industry have the potential to cause millions of infections via food consumption.…”