Food protein‐induced proctocolitis and enteropathy

Tam, Jonathan S.

doi:10.2500/jfa.2020.2.200017

Cited by 6 publications

(5 citation statements)

References 24 publications

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“…Food proteininduced enteropathy (FPE) 3,4,10,15 • Uncommon a diagnosis specifically impacts the small intestine, most often chronic gastrointestinal symptoms concurrent with chronic ingestion of food trigger, possible to have acute onset of symptoms (<12 h) after ingestion. May be initially confused with celiac disease.…”

Section: • International Fpies Associationmentioning

confidence: 99%

“…For example, Elevated levels of celiac disease antibody in blood and genetic tests for human leukocyte antigen (HLA-DQ2 and HLADQ8) are used to confirm celiac disease or risk, and biopsies can be used to support diagnosis in both celiac disease and FPE. Relatively little is known about non-IgE FA pathophysiology, so the definition for these disorders is established through expert opinion and consensus 3 . A patient’s medical history consistent with non-IgE FA presentation, typically gastrointestinal reactions, is the key factor when considering FA diagnosis.…”

Section: Recognizing Non–ige-mediated Food Allergymentioning

confidence: 99%

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Non–Immunoglobulin E–Mediated Food Allergies

Weston,

Myers

2024

Nutr Today

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In food allergy, there is an unfortunate misconception that all allergies are equally dangerous. This third article on food allergies focuses on non–immunoglobulin E–mediated food allergy, which classically presents in infancy or early childhood and predominantly involves the gastrointestinal tract. Most non–immunoglobulin E–mediated food allergies have a good prognosis, with the majority outgrown in childhood, although a minority of cases do persist into adulthood.

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Section: • International Fpies Associationmentioning

confidence: 99%

Section: Recognizing Non–ige-mediated Food Allergymentioning

confidence: 99%

Non–Immunoglobulin E–Mediated Food Allergies

Weston,

Myers

2024

Nutr Today

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“…Immunologic adverse reactions to foods for which there is no apparent role for IgE include food protein–induced enterocolitis syndrome, protein-induced enteropathy/proctocolitis, and celiac disease , (see “Food protein–induced enterocolitis syndrome” 18 and “Food protein-induced enteropathy and proctocolitis” 19 ). Although allergic proctocolitis symptoms are isolated to the gastrointestinal tract, the other disorders have symptoms and signs beyond the gastrointestinal tract, as described further in those sections of the Primer.…”

Section: Food Allergymentioning

confidence: 99%

Classification of adverse food reactions

Cox¹,

Sicherer²

2020

Journal of Food Allergy

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Foods can induce adverse reactions by a variety of mechanisms. An understanding of the characteristic signs and symptoms and the related mechanisms of adverse food reactions allows the clinician to efficiently diagnose and treat patients. Adverse reactions to foods can be classified based on whether there is a nonimmunologic or immunologic basis for symptoms. Food intolerance, or a nonimmunologic reaction, includes a range of responses to foods that result primarily from an individual’s intrinsic inability to metabolize a component of the food, e.g., lactose sugar in dairy products. Other nonimmunologic adverse reactions may be attributed to food toxins or pharmacologic properties pharmacologic properties of foods themselves. Immunologic adverse reactions, in contrast, involve immune responses to food and are termed food allergy. Food allergy may further be categorized based on the underlying immunopathophysiology as immunoglobulin E (IgE) mediated, non‐IgE mediated, or cell mediated. Some chronic allergic responses involve a combination of immune mechanisms. This review provides a general classification system for adverse food reactions and describes specific conditions.

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“…FPIAP is usually self-limited, with more than half of infants developing tolerance by 1 year of age and almost all developing tolerance by 3 years of age. 21 Tam 22 provides further information in this issue on food-induced proctocolitis.…”

Section: Presentation Evaluation and Management Of Food Allergy In An...mentioning

confidence: 99%

Food allergy and breast-feeding

Pier¹,

Järvinen²

2020

Journal of Food Allergy

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Breast-feeding is currently recommended as the optimal source of nutrition for infants; however, it is known that some individuals can excrete enough food antigens in breast milk to result in allergic reactions in infants, especially those already highly sensitized. These reactions can include non‐immunoglobulin E (IgE) mediated reactions, such as atopic dermatitis or gastrointestinal symptoms, and IgE-mediated reactions, such as anaphylaxis, although rare. Food reactions in infants who are breast-fed is a unique challenge because identifying the culprit foods may be more difficult and special consideration must be taken in ensuring proper nutrition during periods of food avoidance for both the infant and mother. This article reviews what is currently known about food allergy in infants who are breast-fed as well as offers insights into a proposed evaluation.

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Food protein‐induced proctocolitis and enteropathy

Cited by 6 publications

References 24 publications

Non–Immunoglobulin E–Mediated Food Allergies

Non–Immunoglobulin E–Mediated Food Allergies

Classification of adverse food reactions

Food allergy and breast-feeding

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