Food intake and body composition in cancer cachexia

Giacosa, Attilio; Frascio, F.; Sukkar, Samir Giuseppe; Roncella, S.

doi:10.1016/0899-9007(95)00065-8

Cited by 25 publications

(16 citation statements)

References 22 publications

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“…The depletion of body fat is the reason for the rapid weight loss in cancer cachexia [45], especially in pancreatic cancer [42][43][44]. Decreased food intake associated with reduction of BCM and body fat differentiate cancer cachexia from chronic starvation.…”

Section: Discussionmentioning

confidence: 99%

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Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer

Niedergethmann

Shang

Soliman

et al. 2006

Langenbecks Arch Surg

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Section: Discussionmentioning

confidence: 99%

“…Indeed, body fat is the component that is preferentially depleted in noncancer starvation. The effect of refeeding on body composition in malnourished cancer patients is still debatable [45]. In fact, an inability to use nutrients effectively is one distinguishing feature of cancer cachexia.…”

Section: Discussionmentioning

confidence: 99%

Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer

Niedergethmann

Shang

Soliman

et al. 2006

Langenbecks Arch Surg

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show abstract

“…Radiation damage may improve over months and some may never return to the level prior to treatment (24). During the course of treatment, patients also appear nausea and vomiting, anorexic, with full bilge, diarrhea, catarrh, stomatitis, pain and other symptoms (25). The patient's interest in food and food preparation, and the ability to eat are influenced, which reduces the nutrient intake, resulting in malnutrition.…”

Section: Discussionmentioning

confidence: 99%

Effects of nutritional intervention in head and neck cancer patients undergoing radiotherapy: A prospective randomized clinical trial

Kang

Huang

et al. 2016

Molecular and Clinical Oncology

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Abstract. Head and neck malignant tumors have numerous locations of the disease. After patients receive radiotherapy, their nutritional status is very poor, thus the curative effect is unsatisfactory. The aims of the present study were to investigate and analyze the nutritional status of patients with head and neck cancer undergoing radiotherapy (RT) in order to provide positive nutrition intervention for assisting the radiotherapy effect. A total of 40 patients with head and neck cancer were selected using a method of subjective global assessment (SGA) to assess nutritional status, including calorie intake and energy expenditure. In a randomized, controlled study, 20 patients received intensive dietary counseling and nutritional therapy (G1) and 20 received regular dietary as controls (G0) preradiotherapy and postradiotherapy. The primary endpoint was calorie intake and energy expenditure. The secondary endpoint was SGA rating with nutritional therapy. At the end of RT, energy intake showed a net increase in G1 (1,691±301 kcal) compared with that in G0 (1,066±312 kcal) (P<0.05); energy expenditure increased in G1 (1,673±279 kcal) compared with G0 (1,490±298 kcal) (P<0.05). The prevalence of severe malnutrition following radiotherapy was significantly different between the two study groups (10 patients in G0 and 4 patients in G1; P<0.05). The number of the normal malnutrition patients postRT in G0 decreased from 4 to 2 and conversely, in G1 it increased from 3 to 6 (P<0.05). In conclusion, patients with head and neck cancer were most malnutritioned, which impacted on clinical outcome. Timely nutritional intervention can effectively prevent weight loss and muscle wasting.Additionally, it may improve quality of life by decreasing the frequency of severe malnutrition.

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“…Cancer cachexia is a debilitating weight loss syndrome characterised by disease-induced starvation and wasting (Giacosa 1994). Whilst there is no universally accepted definition of cachexia, the clinical signs that form the hallmark of cancer associated cachexia are anorexia and extreme weight loss.…”

Section: B a C K G R O U N Dmentioning

confidence: 99%

Oral eicosapentaenoic acid (an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia

Dewey¹,

Baughan²,

Dean³

et al. 2004

Cochrane Database of Systematic Reviews

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Food intake and body composition in cancer cachexia

Cited by 25 publications

References 22 publications

Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer

Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer

Effects of nutritional intervention in head and neck cancer patients undergoing radiotherapy: A prospective randomized clinical trial

Oral eicosapentaenoic acid (an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia

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