Food Insecurity and Aging Outcomes in Older Adults Living with HIV

Hessol, Nancy A.; Zepf, Roland; Zobell, Elizabeth; Weiser, Sheri D.; John, M.

doi:10.1007/s10461-017-1838-y

Cited by 28 publications

(26 citation statements)

References 50 publications

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“…Four studies (n = 51,541) ( Fig. 4) provided sufficient data to calculate an odds ratio of 2.41 [95% CI 1.81-3.22, Q(df = 3) = 8, I 2 = 63%], 39,52,77,82 while three (n = 825) ( Fig. 5) yielded a Hedges' g = 0.50 [95% CI 0.34-0.66, Q(df = 2) = 1.2, I 2 = 0%].…”

Section: Results Of Individual Studies and Synthesis Of Resultsmentioning

confidence: 99%

A Systematic Review and Meta-analysis of Depression, Anxiety, and Sleep Disorders in US Adults with Food Insecurity

et al. 2019

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INTRODUCTION: A large number of peer-reviewed studies, with various methodologies and populations, have addressed the effects of food insecurity (FIS) on mental health conditions such as depression, anxiety, and sleep disorders. There are currently, however, no published systematic assessments or meta-analyses of this literature. METHODS: A systematic search of the literature was conducted in PubMed, PsycInfo, Embase, Scopus, and Web of Science. Cross-sectional studies assessing the association between food insecurity and depression, anxiety, or sleep disorders were identified. For each of the three health outcomes, we extracted (or calculated when possible) the following effect sizes: odds ratio (OR), Hedges' g, Pearson correlation coefficients r, or bivariate coefficients. Then, for each mental health-outcome/effect-size pair, the available studies were combined using the random effect model. Heterogeneity, publication bias, and subgroup dependence, for each meta-analysis, were also assessed. RESULTS: Fifty-seven studies provided cross-sectional data on the relationship between FIS and depression (n = 169,433), 13 on anxiety and psychological distress (n = 91,957), and 8 studies provided data on sleep disorders (n = 85,788). Meta-analysis showed that FIS is associated with an increased risk of testing positive for depres

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Section: Results Of Individual Studies and Synthesis Of Resultsmentioning

confidence: 99%

A Systematic Review and Meta-analysis of Depression, Anxiety, and Sleep Disorders in US Adults with Food Insecurity

et al. 2019

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“…Exploration of the present model of biological aging in other datasets is needed, as well as further longitudinal studies of ageing and health among people with HIV. Further research is needed on the intersection between frailty, HIV, and related, acquired age-associated risk states, such as diabetes [ 46 ], COPD [ 47 ], social isolation [ 48 ], and food insecurity [ 49 , 50 ]. We identified factors across multiple domains that were predictive of health transitions, and not all were specific to HIV infection.…”

Section: Discussionmentioning

confidence: 99%

Predictors of transitions in frailty severity and mortality among people aging with HIV

et al. 2017

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BackgroundPeople aging with HIV show variable health trajectories. Our objective was to identify longitudinal predictors of frailty severity and mortality among a group aging with HIV.MethodsExploratory analyses employing a multistate transition model, with data from the prospective Modena HIV Metabolic Clinic Cohort Study, based in Northern Italy, begun in 2004. Participants were followed over four years from their first available visit. We included all 963 participants (mean age 46.8±7.1; 29% female; 89% undetectable HIV viral load; median current CD4 count 549, IQR 405–720; nadir CD4 count 180, 81–280) with four-year data. Frailty was quantified using a 31-item frailty index. Outcomes were frailty index score or mortality at four-year follow-up. Candidate predictor variables were baseline frailty index score, demographic (age, sex), HIV-disease related (undetectable HIV viral load, current CD4+ T-cell count, nadir CD4 count, duration of HIV infection, and duration of antiretroviral therapy [ARV] exposure), and behavioral factors (smoking, injection drug use (IDU), and hepatitis C virus co-infection).ResultsFour-year mortality was 3.0% (n = 29). In multivariable analyses, independent predictors of frailty index at follow-up were baseline frailty index (RR 1.06, 95% CI 1.05–1.07), female sex (RR 0.93, 95% CI 0.87–0.98), nadir CD4 cell count (RR 0.96, 95% CI 0.93–0.99), duration of HIV infection (RR 1.06, 95% CI 1.01–1.12), duration of ARV exposure (RR 1.08, 95% CI 1.02–1.14), and smoking pack-years (1.03, 1.01–1.05). Independent predictors of mortality were baseline frailty index (OR 1.19, 1.02–1.38), current CD4 count (0.34, 0.20–0.60), and IDU (2.89, 1.30–6.42).ConclusionsDemographic, HIV-disease related, and social and behavioral factors appear to confer risk for changes in frailty severity and mortality among people aging with HIV.

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“…These challenges encompass socioeconomics [ 5 , 6 ], depression [ 7 ], housing [ 8 ] and food security [ 9 , 10 ]. Older adults with HIV experience similar challenges [ 11 – 14 ]. In addition, they face issues of sexuality [ 15 , 16 ], high risk behaviours [ 17 , 18 ], premature age-related comorbidities [ 19 ], early frailty [ 20 ], poor physical function [ 21 ] and shortened life expectancy [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Unmet basic needs negatively affect health-related quality of life in people aging with HIV: results from the Positive Spaces, Healthy Places study

et al. 2018

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BackgroundBasic needs (e.g., food security and stable housing) are important determinants of health and well-being, yet their impact on health-related quality of life (HRQoL) in the context of HIV and aging has not been systematically investigated.MethodsMultiple linear regression models examined the relationship between unmet basic needs, and physical and mental HRQoL by age strata (20-34, 35-49 and 50+) in a cross-sectional sample of 496 people living with HIV in Ontario, Canada.ResultsAn overwhelming majority of participants (87%) reported unmet needs related to food, clothing or housing. The prevalence of unmet basic needs in the two older groups appeared to be lower than among younger participants, but the difference did not reach statistical significance. The presence of unmet basic needs predicted substantially lower mean physical health and mental health summary scores in the two oldest groups. Notably, age moderated the influence of unmet basic needs on HRQoL.ConclusionsThe availability and accessibility of food security, appropriate clothing and stable housing for people living with HIV who are aging need to become a higher priority for program planners and decision makers.

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Food Insecurity and Aging Outcomes in Older Adults Living with HIV

Cited by 28 publications

References 50 publications

A Systematic Review and Meta-analysis of Depression, Anxiety, and Sleep Disorders in US Adults with Food Insecurity

A Systematic Review and Meta-analysis of Depression, Anxiety, and Sleep Disorders in US Adults with Food Insecurity

Predictors of transitions in frailty severity and mortality among people aging with HIV

Unmet basic needs negatively affect health-related quality of life in people aging with HIV: results from the Positive Spaces, Healthy Places study

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