Food‐induced anaphylaxis caused by ingestion of royal jelly

Abstract

We report a case of food-induced anaphylaxis caused by ingestion of royal jelly. After taking royal jelly and several other medicinal products, a 33-year-old Japanese male developed severe facial pruritus and erythema, followed by vertigo, numbness in his fingers, generalized pruritus, wheals, dyspnea, wheezing and impaired consciousness. He was treated with corticosteroid and fluid therapy, and his symptoms subsided. Upon allergy testing, his only positive reaction was to royal jelly. Given the clinical symptoms and the positive prick test to royal jelly, a diagnosis of anaphylaxis due to the ingestion of royal jelly was made. In this paper, we describe this case and review the relevant published work.

ANTIBACTERIAL ACTIVITY OF ROYAL JELLY AND RAPE HONEY AGAINST Aeromonas hydrophila (ATCC 7965)

“…Some authors recommend testing for allergic reactions prior to clinical investigations (Leung et al, 1997;Lombardi et al, 1998;Takahama and Shimazu, 2006). In the future it is important to do additional investigations about the specific antibacterial activity of strong insoluble polyphenolprotein complexes in royal jelly and rape honey mixes for different microorganisms.…”

“…The antibacterial activity of the peptide Royalisin against Gram-positive bacteria has been known since 1990 (Fujiwara et al, 1990;Shen et al, 2010). On the other hand, RJ may cause allergic reactions in humans, asthma, fatal anaphylaxis, thus this product remains non-approved for use in most countries (Leung et al, 1997;Lombardi et al, 1998;Takahama and Shimazu, 2006).…”

In Vitro Antibacterial Activity of Royal Gelly Against Pathogen Escherichia Coli

“…RJ may cause allergic reactions in humans, asthma, to even fatal anaphylaxis, thus this product remains unaffordable in most countries (Leung et al, 1997;Lombardi et al, 1998;Takahama and Shimazu, 2006).…”

Antibacterial effect of Royal gelly, mix from Royal jelly and rape honey (1:100), rape and oak honeydew honeys against Escherichia coli (ATCC 25922)

“…RJ may cause allergic reactions in humans, asthma and even fatal anaphylaxis; thus this product remains unaffordable in most countries (Leung et al, 1997;Lombardi et al, 1998;Takahama and Shimazu, 2006). From another perspective, it was found to have more positive effect of RJ: imunostimulating, activating vegetative and central neural systems etc.…”