Food Consumption is Associated with Hyperuricemia in Boys

Abstract

Introduction Hyperuricemia is related to health issues among children and adolescents, once the uric acid concentration is associated with metabolic syndrome, hypertension, insulin resistance, obesity, and dyslipidemia. However, few studies are addressing uric acid levels and food uptake in this age group. Aim To verify the association between food consumption and uric acid in children and adolescents. Methods This is a cross-sectional study developed with 2335 children and adolescents of both genders aged 6-17 years old. Blood collection was performed after 12 h of fasting. Uric acid values were classified according to tertiles, in which the highest tertile was considered as hyperuricemia. Food consumption was evaluated by weekly consumption frequency questionnaire. Pearson correlation and logistic binary regressions were used for statistical analysis. Models were adjusted for age, systolic blood pressure, body mass index (BMI), and skin color/ethnicity. Results It was found an association between red meat consumption and hyperuricemia only in boys in the crude model (OR = 1.56; 95% CI 1.12; 2.18). Also, there was an association between pasta (OR = 1.52; 95% CI 1.11; 2.10) with hyperuricemia in boys, when adjusted age, systolic blood pressure, BMI, and skin color/ethnicity. Conclusion The knowledge of food patterns which are predisposing factors for the increase in serum uric acid levels is important for the implementation of strategies and public health policies for health promotion among children and adolescents.

Hyperurikämie, Gicht und Herz – eine kritische Diskussion im Licht der aktuellen Literatur

“…B. fleischreiche Kost) und auch die durch endogenen Zelluntergang/-abbau freiwerdenden Purine werden z.T. wieder genutzt, überwiegend aber in der Leber in Harnsäure umgewandelt, um schließlich überwiegend renal eliminiert zu werden [2]. Kommt es dauerhaft entweder zu einer verstärken externen Zufuhr mit der Nahrung, zu einem erhöhten endogenen Anfall von Purinen (z.…”