Food Aversion during Cancer Treatment: A Systematic Review

Pereira, Aline de Araújo; Reis, Emylliane Santana Dos; Guilarducci, Mariana Julião; Oliveira, Julia Silva E; Gomes, Júnia Maria Geraldo

doi:10.1080/01635581.2022.2129079

Cited by 1 publication

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References 41 publications

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“…This hypothesis is consistent with some patterns of food aversions and preferences in pregnancy, such as avoidance of meat, and with data showing that women with NVP have reduced rates of some birth defects [ 32 ]. However, nausea and vomiting due to other causes, such as cancer treatments, induce similar food aversions [ 33 ], indicating that such effects are not specific to pregnancy. Moreover, the association of lower NVP with higher rates of birth defects may be due to reduced embryo viability causing both outcomes, rather than to a causal chain from NVP, to food aversions, to birth defects.…”

Section: The Adaptive Significance Of Gdf15mentioning

confidence: 99%

Nausea, vomiting and conflict in pregnancy

Crespi

2024

Evolution, Medicine, and Public Health

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Nausea and vomiting in pregnancy (NVP) is heritable, common, and aversive, and its extreme, hyperemesis gravidarum (HG), can be highly deleterious to the mother and fetus. Recent influential studies have demonstrated that HG is caused predominantly by high levels of Growth-Differentiation Factor 15 (GDF15), a hormone produced by the placenta in substantial amounts. This work has led to calls for therapeutic modulation of this hormone, to reduce GDF15 levels and ameliorate HG risk. I describe three main lines of evidence relevant to the hypothesis that GDF15 production is typically adaptive for the fetus, in the context of enhanced placental invasion, reduced rates of miscarriage and preterm birth, and higher birth weight. These considerations highlight the medical implications of maternal-fetal conflict, in the context of tradeoffs between aversive symptoms during gestation, rare disorders of pregnancy with major adverse effects, and moderate fitness-enhancing benefits to fetuses.

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Section: The Adaptive Significance Of Gdf15mentioning

confidence: 99%

Nausea, vomiting and conflict in pregnancy

Crespi

2024

Evolution, Medicine, and Public Health

View full text Add to dashboard Cite

show abstract

Food Aversion during Cancer Treatment: A Systematic Review

Cited by 1 publication

References 41 publications

Nausea, vomiting and conflict in pregnancy

Nausea, vomiting and conflict in pregnancy

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