Food and Gastroesophageal Reflux Disease

Surdea-Blaga, Teodora; Negrutiu, D.-E.; Palage, Mariana; Dumitraşcu, Dan L.

doi:10.2174/0929867324666170515123807

Cited by 65 publications

(46 citation statements)

References 79 publications

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“…Specifically, foods with a high fat content have been shown to increase the number of GERD episodes significantly when compared to foods with normal fat content . Similarly, spicy food may induce heartburn, but the literature is not conclusive . Culinary differences across the country, such as the popularity of spicy and deep fried foods in the South, could contribute to regional variability in risk factors and subsequent prescribing differences observed.…”

Section: Discussionmentioning

confidence: 99%

Practice patterns of reflux medication prescriptions in otolaryngology compared to other specialties

Luetzenberg

Jiang

2019

The Laryngoscope

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Objectives/Hypothesis To describe the trends in proton pump inhibitor (PPI) prescription rates and durations and compare them to those of H2‐receptor antagonists (H2RAs) between 2013 and 2016 in otolaryngology, gastroenterology, and family practice, following the increasing publications on PPI adverse effects and inappropriate prescribing. Study Design Retrospective review of publicly available Medicare Part D prescribing data. Methods PPI and H2RA prescription and beneficiary data were obtained through the Centers for Medicare and Medicaid Services website. For prescription rates, 30‐day fill counts were analyzed nationally and regionally per 10,000 Medicare members. Days supply per beneficiary was examined to show average prescription durations. Results were compared between otolaryngology, gastroenterology, and family practice. Medication‐related economic burden per year was calculated based on reported drug cost. Results From 2013 to 2016, PPI 30‐day fill counts remained stable, whereas H2RA prescription rates increased by up to 62% per 10,000 Medicare beneficiaries. The South consistently prescribed two to three times as much antireflux medication as the lowest prescribing region over time and across all three specialties. The days supply per beneficiary remained stable and ranged from an average of 128 to 203 days depending on the specialty. Antireflux medication‐related healthcare cost decreased steadily. Conclusions Despite numerous publications describing a multitude of adverse events and inappropriate prescribing patterns of PPIs in the past decade, prescription rates and durations per beneficiary have remained stable in the fields of otolaryngology, gastroenterology, and family practice. Additionally, H2RA prescriptions have increased from 2013 to 2016. Level of Evidence NA Laryngoscope, 130:321–327, 2020

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Section: Discussionmentioning

confidence: 99%

Practice patterns of reflux medication prescriptions in otolaryngology compared to other specialties

Luetzenberg

Jiang

2019

The Laryngoscope

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“…Regular intake of chocolate induces the gastric acid reflux with increasing lower esophageal exposure to acid. Spicy foods might as well induce heartburn, but the mechanism has not known yet [ 34 ]. The consumption of fast food is considered as a risk factor for acid reflux [ 35 , 36 ].…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Gastroesophageal Reflux Disease in Saudi Arabia

et al. 2017

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BackgroundGastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal tract diseases worldwide. GERD has an effect on the patients’ quality of life as well as the health care system that can be prevented by identifying its risk factors among the population. Hence, we applied this study to assess the GERD’s risk factors in Saudi Arabia.MethodsA cross-sectional study was designed to assess the GERD’s risk factors among the community of Saudi Arabia. The sample was collected randomly during the period from November to December 2016. Through a self-administered validated GERD questionnaire (GerdQ), GERD was diagnosed. Then, the GERD’s risk factors were assessed among all participants. The data were analyzed using Statistical Package for Social Sciences version 21.0; the Student’s t-test was used to assess the association of GERD and risk factors.ResultsA total of 2,043 subjects participated in the study. The characteristics and behaviors of participants statistically significant with GERD were positive family history (39.3%), obese (body mass index > 30 kg/m2) (39.4%), not performing weekly regular physical activities ≥ 30 min (31.1%) and smoking (39.3%). GERD was commonly noticed in participants on analgesics (38.4%), not taking fibers (37.4%), drinking tea (33.4%), eating greasy (31.2%) and fast food (32.7%), and these were statistically significant with GERD (P ≤ 0.05).ConclusionThe characteristics and behaviors associated with GERD in Saudi population are family history of GERD, obesity, sedentary lifestyle and smoking. Other common risk factors correlated with GERD are analgesics intake, no fibers intake, drinking tea, greasy and fast food intake.

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“…Certain nutrients such as fat intake as well as food such as lemons or orange juice, spicy food, garlic, coffee, and alcohol have been thought to increase the frequency of GERD symptoms . We found that nGER symptoms became more severe with more frequent high‐fat diet and carbonated beverages.…”

Section: Discussionmentioning

confidence: 66%

Survey of nocturnal reflux in patients with gastroesophageal reflux disease in China

Zhang

Hou

Zou

et al. 2019

J of Digest Diseases

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Objective To evaluate current diagnosis and treatment of patients with nocturnal gastroesophageal reflux (nGER). Methods This multicenter observational study was conducted in 44 hospitals in China from May 2017 to February 2018. Outpatients with nGER were recruited and their relevant data were collected using a questionnaire, including age, gender, body mass index, history of smoking and alcohol consumption, comorbid diseases, lifestyle, self‐reported health status, medical history, nGER symptoms and severity, Hospital Anxiety Depression Scale, Pittsburgh Sleep Quality Index, diagnosis and treatment choices. The study was registered on the Chinese Clinical Trial Registry (no. ChiCTR1800017525). Results The study included 4978 individuals, with valid questionnaires collected from 4448 patients (89.4%). The symptoms of heartburn and regurgitation were more severe at night than during the day (P < 0.05). Age and body mass index were positively correlated with reflux severity at night and during the day (P < 0.05). The severity of nGER was positively associated with lifestyle factors such as smoking, a high‐fat diet, carbonated beverage consumption, late supper (later than 9 pm), and snoring (all P < 0.05). Night‐time heartburn and regurgitation were related with sleep disorder. Conclusions Lifestyle factors are associated with nGER severity, and nGER affects sleep quality. It will be beneficial to popularize and strengthen the diagnosis and treatment of nGER.

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Food and Gastroesophageal Reflux Disease

Cited by 65 publications

References 79 publications

Practice patterns of reflux medication prescriptions in otolaryngology compared to other specialties

Practice patterns of reflux medication prescriptions in otolaryngology compared to other specialties

Risk Factors for Gastroesophageal Reflux Disease in Saudi Arabia

Survey of nocturnal reflux in patients with gastroesophageal reflux disease in China

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