Food and functional dyspepsia: a systematic review

Duncanson, Kerith; Talley, Nicholas J.; Walker, Marjorie M.; Burrows, Tracy

doi:10.1111/jhn.12506

Cited by 99 publications

(87 citation statements)

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“…The relationship between functional dyspepsia and SR‐NCWS is less clear. Both gluten and fructans have been associated with functional dyspepsia in observational studies, and some patients with functional dyspepsia were found to have formal non‐coeliac gluten or wheat sensitivity in dietary crossover trials . Duodenal eosinophilia occurs in people with functional dyspepsia or non‐coeliac gluten or wheat sensitivity, suggesting a pathophysiological link …”

Section: Discussionmentioning

confidence: 99%

Incidence and prevalence of self‐reported non‐coeliac wheat sensitivity and gluten avoidance in Australia

Potter

Jones

Walker

et al. 2020

Medical Journal of Australia

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Objectives To determine the incidence of self‐reported non‐coeliac wheat sensitivity (SR‐NCWS) and factors associated with its onset and resolution; to describe the prevalence of factors associated with gluten avoidance. Design Longitudinal cohort study; analysis of responses to self‐administered validated questionnaires (Digestive Health and Wellbeing surveys, 2015 and 2018). Setting, participants Subset of an adult population sample randomly selected in 2015 from the electoral rolls for the Newcastle and Gosford regions of New South Wales. Main outcome measures Prevalence of SR‐NCWS (2015, 2018) and incidence and resolution of SR‐NCWS, each by demographic and medical factors; prevalence of gluten avoidance and reasons for gluten avoidance (2018). Results 1322 of 2185 eligible participants completed the 2018 survey (response rate, 60.5%). The prevalence of SR‐NCWS was similar in 2015 (13.8%; 95% CI, 12.0–15.8%) and 2018 (13.9%; 95% CI, 12.1–15.9%); 69 of 1301 respondents (5.3%) reported developing new onset (incident) SR‐NCWS between 2015 and 2018 (incidence, 1.8% per year). Incident SR‐NCWS was significantly associated with a diagnosis of functional dyspepsia, and negatively associated with being male or older. Gluten avoidance was reported in 2018 by 24.2% of respondents (20.5% partial, 3.8% complete avoidance); general health was the most frequent reason for avoidance (168 of 316 avoiders, 53%). All 13 participants with coeliac disease, 56 of 138 with irritable bowel syndrome (41%), and 69 of 237 with functional dyspepsia (29%) avoided dietary gluten. Conclusions The prevalence of SR‐NCWS was similar in 2015 and 2018. Baseline (2015) and incident SR‐NCWS (2018) were each associated with functional gastrointestinal disorders. The number of people avoiding dietary gluten exceeds that of people with coeliac disease or SR‐NCWS, and general health considerations and abdominal symptoms are the most frequently reported reasons for avoidance.

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Section: Discussionmentioning

confidence: 99%

Incidence and prevalence of self‐reported non‐coeliac wheat sensitivity and gluten avoidance in Australia

Potter

Jones

Walker

et al. 2020

Medical Journal of Australia

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“…Often, these are sought out by readers who want to capture the overview of a topic and so, by stating that it is a review in your title, you draw your work to their attention. Food and functional dyspepsia: a systematic review , for example, leaves no doubt about the content of the paper.…”

Section: Think About What Will Sell Your Papermentioning

confidence: 99%

Editorial: How to Write

Langley‐Evans

2019

J Human Nutrition Diet

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“…При высокой резистентности к фторхинолонам в данном регионе рассматриваются комбинация «ИПП + рифабу-тин + препарат висмута» или другие схемы [23].…”

Section: антихеликобактерная терапияunclassified

“…Развитие микроскопиче-ского воспаления может быть связано с перенесенной пищевой токсикоинфекцией [21], повторными воздействи-ями раздражителей, а также хеликобактерной инфекцией (в последнем случае более корректно, как уже говорилось выше, применять термин «диспепсия, ассоциированная с инфекцией H. pylori») [22]. Среди пищевых факторов, кото-рые могут способствовать развитию микроскопического воспаления при ФД, основная роль принадлежит повы-шенному потребления жиров, ферментируемых углеводов, пшеницы и, возможно, других компонентов, выступающих в роли аллергенов, а также действию соляной кислоты [19,23,24]. Клинические симптомы становятся более выражен-ными в условиях тревоги, депрессии, на фоне повышения метаболизма в таламусе, островке, поясной извилине [25].…”

unclassified

“…), глютену, олиго-, ди-и моносахаридам, а также температурным воздействиям. Симптомы могут усугубляться при употреблении шокола-да, кофе, газированных напитков, майонеза, орехов, цитрусовых [28]. В основе такой сенситизации лежит повышение возбудимости ваниллоидных рецепторов (transient receptor potential vanilloid, TRPV), которые реа-гируют на данные раздражители [29,30].…”

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Rabeprazole in the treatment of duodenal ulcer desease and functional dyspepsia

Русяев¹,

Шептулин²,

Шульпекова³

et al. 2018

Med. sov.

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M.Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University) RABEPRAZOLE IN THE TREATMENT OF DUODENAL ULCER DESEASE AND FUNCTIONAL DYSPEPSIA The review aims to provide a contemporary view of the pathogenesis and treatment of the most common duodenum diseasesduodenal ulcer disease (DUD) and functional dyspepsia (FD).Due to its unique structure and functions, the duodenum that anatomically represents the initial section of the small intestine differentiates itself from others. The prevalence of DUD is declining in many Western countries due to the widespread introduction of effective anti-Helicobacter therapy and a significant decrease in the prevalence of H pylori infection. However, the ideas about the poly-biological nature of DUD persists and additional risk factors continue to be studied. DUD is manifested by pain/burning feeling in the epigastric region, as well as by symptoms such as early satiety, epigastric filling after eating in the absence of obvious organic changes in the digestive system. The diagnosis of FD is based on the Rome IV criteria. The duodenum plays an important role in its pathogenesis (disorders of gastric accommodation, motor and visceral hypersensitivity). Most patients with FD have microscopic signs of inflammation of the mucous membrane of the postbulbar part of the duodenum -an increased amount of intraepithelial lymphocytes, eosinophils, and signs of increased permeability of the mucous membrane. In all likelihood, these changes are provoked by infection and / or nutritional factors, as well as by exposure to hydrochloric acid. Proton pump inhibitors (prokinetics in postprandial distress syndrome) form the basis of treatment of peptic ulcer and epigastric pain syndrome; all patients with DUD and dyspepsia syndrome infected with H. pylori receive antihelicobacter therapy. Rabeprazole that is characterized by a long and powerful effect and minimal interaction with the cytochrome 2C19 system stands out from the proton pump inhibitors. Conclusion: acid aggression plays a very important role in the pathogenesis of duodenal ulcers diseases and FD; proton pump inhibitors form the basis for the treatment of such patients both in the form of monotherapy and as part of eradication regimens.

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Food and functional dyspepsia: a systematic review

Cited by 99 publications

References 50 publications

Incidence and prevalence of self‐reported non‐coeliac wheat sensitivity and gluten avoidance in Australia

Incidence and prevalence of self‐reported non‐coeliac wheat sensitivity and gluten avoidance in Australia

Editorial: How to Write

Rabeprazole in the treatment of duodenal ulcer desease and functional dyspepsia

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