Food allergy QoL questionnaire for children aged 0–12 years: content, construct, and cross‐cultural validity

DunnGalvin, Audrey; BlokFlokstra, B. M. J. de; Burks, A. Wesley; Dubois, Anthony; Hourihane, Jonathan

doi:10.1111/j.1365-2222.2008.02978.x

Cited by 191 publications

(233 citation statements)

References 29 publications

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“…Recently, as part of the EuroPrevall project, the first self-administered HRQL questionnaires specific for food allergy have been developed and validated: the Food Allergy Quality of Life Questionnaire-Child Form, -Teenager Form and -Adult Form (FAQLQ-CF, -TF, -AF). The FAQLQs showed good validity, internal consistency and discriminative abilities [13][14][15][16], but test-retest reliability was not extensively investigated.…”

Section: Introductionmentioning

confidence: 99%

Test–retest reliability of the Food Allergy Quality of Life Questionnaires (FAQLQ) for children, adolescents and adults

et al. 2009

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Objective The self-administered Food Allergy Quality of Life Questionnaire-Child Form (FAQLQ-CF), -Teenager Form (FAQLQ-TF) and -Adult Form (FAQLQ-AF) were recently developed within EuroPrevall, a multi-centred study of food allergy in Europe. The primary aim of this study was to evaluate the test-retest reliability of the FA-QLQ-CF, -TF and -AF. Methods One hundred and one Dutch patients (31 children, 34 adolescents and 36 adults) completed the FAQLQ twice with a 10-14 day interval. The intraclass correlation coefficient (ICC), Lin's concordance correlation coefficient (CCC) and Bland-Altman plots were used to assess testretest reliability. Results Test-retest reliability was excellent with ICCs and CCCs above 0.907, 0.975 and 0.951 for the FAQLQ-CF, -TF and -AF, respectively. Bland-Altman plots showed that the mean differences of the test and re-test were all close to zero for the FAQLQs. Conclusions The FAQLQs are reliable over a short time interval. The FAQLQs are not only excellent tools for group comparison studies, but also for monitoring individual patients.

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Section: Introductionmentioning

confidence: 99%

Test–retest reliability of the Food Allergy Quality of Life Questionnaires (FAQLQ) for children, adolescents and adults

et al. 2009

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“…Being a disease specific questionnaire, it has the advantage of showing no ceiling effect, which on the contrary, is present in the generic quality of life questionnaires due to the fact that most of the patients reach the highest score in generic questions, not related with the specific problems of their disease (l, 5). In addition, a disease-specific questionnaire can be used in longitudinal studies and it is suitable for the assessment of changes in the quality of life due to treatment interventions (4). The objective of our pilot study was to apply the questionnaire to s.CARRARO ET AL. assess whether and how quality of life changes in children allergic to cow milk following a specific oral immunotherapy (OIT) protocol.…”

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confidence: 99%

Impact and Oral Immunotherapy on Quality of Life in Children with Cow Milk Allergy: A Pilot Study

Carraro

Frigo

Perin

et al. 2012

Int J Immunopathol Pharmacol

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Quality of life is negatively affected in children with food allergy. Oral immunotherapy is an approach to food allergy that leads to patient desensitization by administering gradually increasing amounts of a given food allergen. The aim of this pilot study is to evaluate how oral immunotherapy affects quality of life in children allergic to cow milk proteins. Thirty children (aged 3-12 years) with cow milk allergy were recruited. Their parents were provided with a validated disease specific quality oflife questionnaire (the food allergy quality of life questionnaire -parent form, FAQLQ-PF) before and again 2 months after completing an oral immunotherapy protocol with cow milk. A significant improvement in all the investigated domains -emotional impact, food anxiety and social and dietary limitations -was found. The separate analysis of the different age groups demonstrated that the emotional impact and the foodrelated anxiety improved in children older than 4, while the social domains improved in each age group. In this pilot experience, oral immunotherapy significantly improves quality of life in children with cow milk allergy. The improvement seems particularly evident in children over 4 years old, who are most likely to benefit from the oral immunotherapy approach. Further placebo-controlled studies are needed to confirm these preliminary results.Food allergy is a common problem in children for which at the moment there are no standard curative treatments, so that the management of food allergy is mainly based on food avoidance and emergency treatment in the event of an accidental exposure (l). The need to carefully avoid a given food and fears of unintentional exposure pose limitations on a person's social life, negatively affecting the quality of life (2, 3). Pediatric studies have confirmed that quality of life suffers both in the children affected, at all ages, and in their parents (2, 3). DunnGalvin et al. validated the first food allergy specific questionnaire that allows parents to report children's QoL from the child's perspective (food allergy quality of life questionnaire -parent form, FAQLQ-PF) (4). Being a disease specific questionnaire, it has the advantage of showing no ceiling effect, which on the contrary, is present in the generic quality of life questionnaires due to the fact that most of the patients reach the highest score in generic questions, not related with the specific problems of their disease (l, 5). In addition, a disease-specific questionnaire can be used in longitudinal studies and it is suitable for the assessment of changes in the quality of life due to treatment interventions (4). The objective of our pilot study was to apply the questionnaire to

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“…Four papers were reviewed for the development and validation of the FA-QLQ-CF in this review (9,10,15,16).…”

Section: Study Selectionmentioning

confidence: 99%

Disease‐specific health‐related quality of life instruments for IgE‐mediated food allergy

Salvilla

Dubois

Blok

et al. 2014

Allergy

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This is one of seven interlinked systematic reviews undertaken on behalf of the European Academy of Allergy and Clinical Immunology as part of their Guidelines for Food Allergy and Anaphylaxis, which focuses on instruments developed for IgE-mediated food allergy. Disease-specific questionnaires are significantly more sensitive than generic ones in measuring the response to interventions or future treatments, as well as estimating the general burden of food allergy. The aim of this systematic review was therefore to identify which disease-specific, validated instruments can be employed to enable assessment of the impact of, and investigations and interventions for, IgE-mediated food allergy on health-related quality of life (HRQL). Using a sensitive search strategy, we searched seven electronic bibliographic databases to identify disease-specific quality of life (QOL) tools relating to IgE-mediated food allergy. From the 17 eligible studies, we identified seven disease-specific HRQL instruments, which were then subjected to detailed quality appraisal. This revealed that these instruments have undergone formal development and validation processes, and have robust psychometric properties, and therefore provide a robust means of establishing the impact of food allergy on QOL. Suitable instruments are now available for use in children, adolescents, parents/caregivers, and adults. Further work must continue to develop a clinical minimal important difference for food allergy and for making these instruments available in a wider range of European languages.The term 'food allergy' refers to the subgroup of foodtriggered reactions in which immunologic mechanisms have been implicated, whether immunoglobulin E (IgE)-mediated, non-IgE-mediated, or involving a combination of IgE-and non-IgE-mediated etiologies (1). This review focuses on food allergy that is likely to have an IgE-mediated etiology.Allergy 69 (2014) 834-844

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Food allergy QoL questionnaire for children aged 0–12 years: content, construct, and cross‐cultural validity

Abstract: The FAQLQ-PF is psychometrically robust, with excellent reliability and validity.

Cited by 191 publications

References 29 publications

Test–retest reliability of the Food Allergy Quality of Life Questionnaires (FAQLQ) for children, adolescents and adults

Test–retest reliability of the Food Allergy Quality of Life Questionnaires (FAQLQ) for children, adolescents and adults

Impact and Oral Immunotherapy on Quality of Life in Children with Cow Milk Allergy: A Pilot Study

Disease‐specific health‐related quality of life instruments for IgE‐mediated food allergy

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