Food Allergy as a Risk Factor for Asthma Morbidity in Adults

Berns, Stephen; Halm, Ethan A.; Sampson, Hugh A.; Sicherer, Scott H.; Busse, Paula J.; Wisnivesky, Juan P.

doi:10.1080/02770900701364031

Cited by 45 publications

(28 citation statements)

References 37 publications

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“…FA has been recently found to be a major risk factor for severe asthma and life-threatening asthma episodes. Several smaller studies have identified food sensitization as a significant risk factor for severe asthma 25, 26. Roberts and colleagues reported 54% of children with asthma requiring intubation for a severe asthma exacerbation had food sensitization, compared with 10% of hospitalized children with asthma at the same hospital 27.…”

Section: Discussionmentioning

confidence: 99%

National prevalence and risk factors for food allergy and relationship to asthma: Results from the National Health and Nutrition Examination Survey 2005-2006

Liu

Jaramillo

Sicherer

et al. 2010

Journal of Allergy and Clinical Immunology

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461

385

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Background The national prevalence and patterns of food allergy (FA) in the United States (US) are not well understood. Objective We developed nationally representative estimates of the prevalence of and demographic risk factors for FA, and investigated associations of FA with asthma, hay fever, and eczema. Methods 8,203 participants in the National Health and Nutrition Examination Survey (NHANES) 2005–2006 had food-specific serum IgE measured to peanut, cow's milk, egg white, and shrimp. Food-specific IgE and age-based criteria were used to define Likely FA (LFA), Possible FA (PFA), and Unlikely FA (UFA), and to develop estimates of clinical FA. Self-reported data were used to evaluate demographic risk factors and associations with asthma and related conditions. Results In the US, the estimated prevalence of clinical FA was 2.5% (peanut 1.3%, milk 0.4%, egg 0.2%, shrimp 1.0%, not mutually exclusive). Risk of PFA/LFA was increased in non-Hispanic blacks (odds ratio (OR) 3.06; 95% confidence interval (CI) 2.14-4.36), males (1.87; 1.32-2.66), and children (2.04; 1.42-2.93). Study participants with doctor-diagnosed asthma (vs. no asthma) exhibited increased risk of all measures of food sensitization. Moreover, in those with LFA, the adjusted OR for current asthma (3.8; 1.5-10.7) and an emergency room (ER) visit for asthma in the past year (6.9; 2.4-19.7) were both notably increased. Conclusion Population-based serologic data on 4 foods indicate an estimated 2.5% of the US population has FA, and increased risk was found for blacks, males, and children. Additionally, FA could be an under-recognized risk factor for problematic asthma.

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Section: Discussionmentioning

confidence: 99%

National prevalence and risk factors for food allergy and relationship to asthma: Results from the National Health and Nutrition Examination Survey 2005-2006

Liu

Jaramillo

Sicherer

et al. 2010

Journal of Allergy and Clinical Immunology

Self Cite

461

385

View full text Add to dashboard Cite

show abstract

“…12 Several studies have indicated that having food allergy may be a risk for problematic asthma, and having asthma may be a risk for severe/fatal food allergy. 12,54,65 Boys appear to be at higher risk than girls, 12 and perhaps women more than men. 66 One study showed a higher risk for increased affluence.…”

Section: Risk Factors Genetics and Racial And Ethnic Differencesmentioning

confidence: 91%

Epidemiology of food allergy

Sicherer

2011

Journal of Allergy and Clinical Immunology

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649

462

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“…In adults, there is evidence that being allergic to more than one food is associated with an increase frequency of oral steroid use and a higher risk of lifetime hospitalizations and emergency department attendances (50). In children, a study showed that having a milk or peanut allergy was associated with an increased number of hospitalizations ( p = 0.009, 0.016) (51).…”

Section: Asthma Triggered By Food Allergensmentioning

confidence: 99%

Asthma, Food Allergy, and How They Relate to Each Other

2017

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The association between atopic diseases is well known, and previous research has shown that having one atopic disease can predispose to having another. The link between asthma and food allergy has been well researched, but the exact relationship between the two atopic conditions is not fully understood. Food allergic infants are at increased risk for the development of asthma and are at risk of food-induced asthmatic episodes and also anaphylaxis. Having a diagnosis of both food allergy and asthma has also been shown to have an effect on the severity of a patient’s disease including being at greater risk of severe asthmatic episodes. Therefore, understanding the relationship between these two conditions in order to treat and manage these children safely is crucial to clinicians.

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Food Allergy as a Risk Factor for Asthma Morbidity in Adults

Abstract: Self-reported allergy to foods was associated with worse outcomes, suggesting that food allergy may be a risk factor for increased asthma morbidity in adults.

Cited by 45 publications

References 37 publications

National prevalence and risk factors for food allergy and relationship to asthma: Results from the National Health and Nutrition Examination Survey 2005-2006

National prevalence and risk factors for food allergy and relationship to asthma: Results from the National Health and Nutrition Examination Survey 2005-2006

Epidemiology of food allergy

Asthma, Food Allergy, and How They Relate to Each Other

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