2007
DOI: 10.1016/s0140-6736(07)61306-3
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Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial

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Cited by 950 publications
(659 citation statements)
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“…It is also possible these results reflect general views in a population where food allergy and food intolerance are relatively prevalent (6 % and 5-20 % respectively in 0-5-year-olds (19) ) and the media attention related to research on these topics (20,21) .…”
Section: Discussionmentioning
confidence: 67%
“…It is also possible these results reflect general views in a population where food allergy and food intolerance are relatively prevalent (6 % and 5-20 % respectively in 0-5-year-olds (19) ) and the media attention related to research on these topics (20,21) .…”
Section: Discussionmentioning
confidence: 67%
“…Recently, synthetic food dyes attracted public concern regarding safety and the adverse effect on human health, particularly neurological functions and behavioral effects. A clinical trial involving a total of 153 three-year-old and 144 eight to nine-year-old children suggested that artificial colorants that contained a mixture of sunset yellow (E110), carmoisine (E122), tartrazine (E102), ponceau 4R (E124), quinoline yellow (E104), and Allura red AC (E129) when combined in the diet with sodium benzoate (E211), resulted in a significant increase of hyperactivity in normal children and aggravated the condition as well at least up to middle childhood [63]. This finding has drawn great interest in exploring natural food colorants such as anthocyanin as a promising alternative to synthetic food dyes.…”
Section: Anthocyanin Pigments As Food Colorants and Additivesmentioning
confidence: 99%
“…These factors may interact and do not always imply causality. They range from divorce (Allen, 2010), poverty (Russell, Ford, Rosenberg, & Kelly, 2013), parenting styles (Johnston, Mash, Miller, & Ninowski, 2012), low maternal education, lone parenthood and reception of social welfare ((Hjern, Weitoft, & Lindblad, 2010), sexual abuse (Weinstein, Staffelbach, & Biaggio, 2000), lack of sleep (Thakkar, 2013), heritability (Larsson, Chang, D’Onofrio, & Lichtenstein, 2013) and perinatal issues (Schmitt & Romanos, 2012) to eczema (Schmitt, Buske-Kirschbaum, & Roessner, 2010), artificial food additives (McCann et al, 2007), mobile phone use (Byun et al, 2013) and growing up in areas with low solar intensity (Arns, van der Heijden, Arnold, & Kenemans, 2013). All these factors and more may play a role when a particular child exhibits impairing hyperactive and inattentive behaviours, and there is no conclusive cause of ADHD.…”
Section: There Is No Single Cause Of Adhdmentioning
confidence: 99%