“…A recent oral double-blind, placebo-controlled food challenge (DBPCFC) study with common food additives in patients with CIU using semiquantitative skin scores as the end point produced positive reactions at rates little different than those seen with placebo. 168 The most recent study, using semi-quantitative skin scores as the end point, concluded the prevalence of food additive sensitivity in CIU patients occurs rarely if at all. 169 These include challenges with monosodium glutamate (MSG), benzoates, parabens, sulfites, butylated hydroxyanisole/butylated hydroxytoluene (BHA/BHT), tartrazine (FD&C Yellow #5, E102), Sunset yellow (FD&C Yellow #6, E110), and aspartame (Nutrasweet).…”