Follow-Up Study of 281 Schizophrenie Patients Treated with High Dosage Fluphenazine Decanoate

Abstract

281 newly admitted female schizophrenic patients were treated with high dosage fluphenazine decanoate intramuscularly, starting with 250 mg per injection together with antiparkinsonian and antidepressant drugs. On a set day the 3 groups ‘with neuroleptics’ (NL) (n = 54), ‘without NL’ (n = 152) and ‘relapsed when without NL’ (n = 42) were compared concerning age, diagnosis, hereditary disposition, first admission and réadmissions, number of admissions and global judgement. From the differences no clear conclusion for practical clinical work could be obtained. The good tolerance is discussed using the list of side effects including tardive dyskinesia and laboratory data.