Follow‐up of Cochlear Implant Use in Patients Who Developed Bacterial Meningitis Following Cochlear Implantation

Mancini, Patrizia; D’Elia, Chiara; Bosco, Ersilia; Seta, Elio De; Panebianco, Valeria; Vergari, Valeria; Filipo, R.

doi:10.1097/mlg.0b013e3181758154

Cited by 14 publications

(12 citation statements)

References 25 publications

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“…El implante coclear (IC) es un procedimiento de rehabilitación quirúrgica en pacientes con hipoacusia severa o profunda. De acuerdo al Instituto Nacional de Sordera y otros problemas de la comunicación e información de la Administración de Drogas y Alimentos (FDA) desde 2005, 100.000 personas en el mundo han recibido un implante coclear (1).…”

Section: Introductionunclassified

Resultados de calidad de vida en niños y adultos con implante coclear

G¹,

Blanco²

2018

Acta otorrinolaringol cir cabeza cuello

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Objetivo: Determinar la calidad de vida en pacientes infantes y adultos que recibieron implante coclear (IC). Diseño: Descriptivo. Materiales y métodos: 47 pacientes usuarios de IC con sordera pre y poslingual a quienes se les realizó encuesta basada en Cuestionario Nijmegen (NCIQ) sobre calidad de vida. Resultados: Promedio de edad para la cirugía de IC: 8,2 años en sordera prelingual y de 47 años en sordera poslingual. La media de PTA y de ganancia auditiva posquirúrgica en ambos grupos fue similar. Hay mejoría posterior a cirugía de IC e inicio de terapia auditiva principalmente en pacientes con sordera prelingual. Conclusiones: Las preguntas basadas en el NCIQ facilitaron la evaluación de calidad de vida posimplante coclear. El costo-beneficio de la cirugía de IC es positivo para la adquisición de lenguaje y en la relación tanto del entorno familiar como en la vida social, así como en la autoestima y la escolaridad.

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Section: Introductionunclassified

Resultados de calidad de vida en niños y adultos con implante coclear

G¹,

Blanco²

2018

Acta otorrinolaringol cir cabeza cuello

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“…Since then, the term "Mondini" has been used as an umbrella term in clinical practice to describe almost any type of congenital cochlear deformity, included temporal bones with a common cavity and an incomplete interscalar septum of the cochlea. And a Mondini cochlea (isolated Mondini) occurs only when the two and a half turns of the cochlea are replaced by a single cavity in the apical region because of the absence of the interscalar septum [9-11]. It is usually bilateral and frequently associated with other inner ear malformations (IEMs) such as cystic expansion of the vestibules and semicircular canal dysplasia.…”

Section: Introductionmentioning

confidence: 99%

Extremely discrepant mutation spectrum of SLC26A4 between Chinese patients with isolated Mondini deformity and enlarged vestibular aqueduct

et al. 2011

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BackgroundMutations in SLC26A4 cause Pendred syndrome (hearing loss with goiter) or DFNB4 (non-syndromic hearing loss with inner ear malformation, such as enlarged vestibular aqueduct or Mondini deformity). The relationship between mutations in SLC26A4 and Mondini deformity without enlarged vestibular aqueduct has not been studied in any Chinese deaf population. The purpose of this study was to assess whether mutations in the SLC26A4 gene cause Mondini deformity without an enlarged vestibular aqueduct (isolated Mondini deformity) in a Chinese population.MethodsIn total, 144 patients with sensorineural hearing loss were included and subjected to high-resolution temporal bone CT. Among them, 28 patients with isolated Mondini dysplasia (MD group), 50 patients with enlarged vestibular aqueduct with Mondini dysplasia (EVA with MD group), 50 patients with enlarged vestibular aqueduct without Mondini dysplasia (EVA group), and 16 patients with other types of inner ear malformations (IEM group) were identified. The coding exons of SLC26A4 were analyzed in all subjects.ResultsDNA sequence analysis of SLC26A4 was performed in all 144 patients. In the different groups, the detection rate of the SLC26A4 mutation differed. In the isolated MD group, only one single allelic mutation in SLC26A4 was found in one patient (1/28, 3.6%). In the EVA with MD group, biallelic and monoallelic SLC26A4 mutations were identified in 46 patients (46/50, 92.0%) and three patients (3/50, 6.0%), respectively. Also, in the EVA group, biallelic and monoallelic SLC26A4 mutations were identified in 46 patients (46/50, 92.0%) and three patients (3/50, 6.0%), respectively. These percentages were identical to those in the EVA plus MD group. Only two patients carried monoallelic mutations of the SLC26A4 gene in the IEM group (2/16, 12.5%). There were significant differences in the frequency of SLC26A4 mutation among the groups (P < 0.001). The detection rate of SLC26A4 mutation in the isolated MD group was significantly lower than in the EVA group (with or without MD; P < 0.001), and there was no significant difference in the detection rate of SLC26A4 between the MD group and IEM group (P > 0.5).ConclusionAlthough mutations in the SLC26A4 gene were frequently found in Chinese EVA patients with and without MD, there was no evidence to show a relationship between isolated MD and the SLC26A4 gene in the Chinese population examined. Hearing impairment in patients with isolated MD may be caused by factors other than mutations in the SLC26A4 gene.

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“…Labyrinthitis ossificans of the ear contralateral to CI might be due to the spread of infection through these same pathways. Osteoneogenesis has been described in cochleae with normal anatomy [Durisin et al, 2010] or congenital malformation but present modiolar structures such as enlarged vestibular aqueduct malformation [Mancini et al, 2008]. To our knowledge, there are no reports of new bone formation described in common cavities (IP-1), where more often recurrent episodes occur [Herther and Schindler, 1985;Ohlms et al, 1990;Phelps et al, 1994;Park et al, 2000;Mylanus et al, 2004;Ben-Shoshan et al, 2007;Lien et al, 2011].…”

Section: Discussionmentioning

confidence: 96%

“…Postmeningitis CI children in general, and those with ossified cochlea in particular, need frequent programming adjustments to maintain performance and MCL threshold which have been shown to be higher in postmeningitic deafness [Eisenberg et al, 1984]. Although a good sound field threshold could be reached in most patients, a reduced number of available electrodes were more pronounced in children with ossified cochlea [Eshraghi et al, 2004;Francis et al, 2008;Mancini et al, 2008]. Increased MCL level threshold might be related to ossification and fibrosis that increase the distance between electrode and the neural interface, but also might be the effect of spiral ganglion neural loss [Klein et al, 2003].…”

Section: Discussionmentioning

confidence: 97%

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Contralateral Implantation in Children Affected by Postimplant Meningitis

et al. 2013

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This study was designed to investigate the indication and advantages of contralateral implantation after postimplant meningitis (piM). Speech perception assessment, most comfortable levels and high-resolution computer tomography were used to monitor cochlear fibrosis/ossification and clinical changes in outcomes in 5 children affected by meningitis after a variable-time post-cochlear implantation. Ipsilateral ossification was found in 3 children, 1 of whom developed delayed contralateral ossification. These children were implanted on the contralateral side as they all showed deterioration of hearing performance. Results from the present paper and literature analysis suggest that, (1) piM can induce ipsilateral and contralateral ossification, (2) meningitis-induced cochlear ossification is more prone to develop in the presence of a normal cochlear structure and (3) contralateral implantation after piM has proven to be effective in restoring performance when a full electrode insertion is accomplished.

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Follow‐up of Cochlear Implant Use in Patients Who Developed Bacterial Meningitis Following Cochlear Implantation

Cited by 14 publications

References 25 publications

Resultados de calidad de vida en niños y adultos con implante coclear

Resultados de calidad de vida en niños y adultos con implante coclear

Extremely discrepant mutation spectrum of SLC26A4 between Chinese patients with isolated Mondini deformity and enlarged vestibular aqueduct

Contralateral Implantation in Children Affected by Postimplant Meningitis

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