Follicular Keratosis of the Chin Treated with 1.24R‐Dihydroxyvitamin D3 Ointment

Abstract

In follicular keratosis of the chin, keratotic follicular papules occur on the chin and jaw due to localized prolonged pressure and friction on the naked skin. We present one patient with this disorder. The dermatoscopic examination revealed many well-demarcated yellow spindle bodies in the patchy lesion. Therapy with 1.24R-dihydroxyvitamin D3 ointment was effective during the treatment but had no residual positive effect.

Topical Tacalcitol for Family Occurrence of Follicular Keratosis of the Chin

“…Histopathological examination usually shows cystic dilated hair follicles containing keratotic basophilic material, positive to Kossa stain, without any inflammation. 1,2 The condition has been reported in 2 brothers previously, 3 and so the present case is at least the second report of familial occurrence. We thus assume a genetic predisposition to develop FKC.…”

“…To our knowledge, only 25 cases of FKC have been reported to date. 1 Usually boys are affected. Some of these patients developed the condition without any evidence of rubbing or friction.…”

Diseases of cutaneous appendages

“…1216 Onset is usually in childhood with remission in adulthood in some patients. 1226 Keratosis pilaris rubra is characterized by substantial erythema, widespread involvement, and persistence after puberty. 1213,1219,1220 Keratosis pilaris itself has also been reported in the ectodermal dysplasias, 1216,1221,1222 and in association with woolly hair.…”

Optical coherence tomography‐assisted diagnosis of follicular keratosis of the chin

“…The only way to heal this skin disease seems to be by avoiding pressure and friction on the lesion. 3,4 In conclusion follicular keratosis of the chin is a benign childhood disease that could be recognized easily using OCT. This observation also suggests that OCT could be helpful in the investigation of other skin diseases involving the hair follicle such as acne or rosacea.…”

“…Follicular keratosis of the chin is a rarely reported entity. 3,4 A mechanic etiology is suspected but the cause is not always obvious. It can be mistaken with other follicular diseases especially folliculotropic mycosis fungoides, and follicular mucinosis.…”