Follicular hybrid cysts with infundibular, isthmic-catagen, and pilomatrical differentiation: a report of 2 patients

May, Steve A.; Quirey, Robert; Cockerell, Clay J.

doi:10.1016/j.anndiagpath.2005.07.016

Cited by 13 publications

(2 citation statements)

References 15 publications

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“…The hybrid cyst refers to cysts with dual linings including variable combinations of epidermoid, trichilemmal, pilomatrical, steatocystoma, and eruptive vellus hair cyst features. 9 , 10 Also, hybrid cysts with follicular and apocrine differentiation have been described. 11 , 12 The more common epidermoid cysts have been described in association with eccrine ducts.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of a Pilar Cyst With Ductal Differentiation

Torous

Binder³

et al. 2015

The American Journal of Dermatopathology

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Pilar cysts are common squamous-lined cysts that typically occur on the scalp. They are believed to arise from the isthmus of anagen hairs or from the sac surrounding catagen and telogen hairs. The authors describe a rare case of a pilar cyst with prominent ductal differentiation, presumably of eccrine derivation. Sweat duct differentiation has been described in a myriad of cutaneous neoplasms and rarely within epidermoid cysts. The authors could only find one other case in the literature describing a pilar cyst with sebaceous and apocrine differentiation. The clinicopathologic findings are described here.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of a Pilar Cyst With Ductal Differentiation

Torous

Binder³

et al. 2015

The American Journal of Dermatopathology

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“…Only two cases displayed pilomatrical differentiation (both in combination with infundibular components). May et al (11) recently described two hybrid cysts each displaying superficial infundibular differentiation, deep trichilemmal differentiation, and pilomatrical differentiation at the base of the cyst. One author has hypothesized that pilomatrical differentiation within a hybrid cyst may be a feature of Gardner’s syndrome (12).…”

Section: Discussionmentioning

confidence: 99%

Hybrid Follicular Cyst (Pilomatrical and Infundibular) Arising Within a Sebaceous Nevus

Rodins

Baillie

2011

Pediatric Dermatology

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A 7-year-old girl presented with a 3-month history of a small blue-brown papule arising within a large sebaceous nevus on her temporal scalp. A punch excision was performed that demonstrated a hybrid follicular cyst. The majority of the cyst wall displayed pilomatrical differentiation consisting of basaloid matrical-type cells with luminal shadow cell keratinization. The matrical epithelium displayed strong membranous, cytoplasmic, and nuclear staining for β-catenin. Only a small component of the wall displayed infundibular differentiation. These findings were consistent with a hybrid follicular cyst predominantly displaying pilomatrical differentiation with only a small component of infundibular lining. The most common tumors arising within sebaceous nevi are the syringocystadenoma papilliferum and trichoblastoma. Follicular cysts with infundibular (sebaceous cyst) and trichilemmal (pilar cyst) differentiation are exceedingly common, although their development within sebaceous nevi appears to be rare. We report a rare case of a hybrid follicular cyst with matrical differentiation occurring within a sebaceous nevus.

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Tumours of Skin Appendages

Calonje

2016

Rook's Textbook of Dermatology, Ninth Edition

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This chapter on cutaneous appendageal tumours covers the spectrum of lesions displaying eccrine, apocrine, sebaceous and follicular differentiation. It includes cysts, hamartomas and benign and malignant tumours. Traditionally, appendageal tumours have been classified according to rigid criteria separating lesions with eccrine, apocrine, sebaceous and follicular differentiation. This separation is clearly artificial and it is now acknowledged that lesions regarded as strictly eccrine may well have apocrine differentiation and lesions classified as purely follicular may exhibit apocrine differentiation reflecting the close embryological relationship between the pilosebaceous unit and the apocrine gland.

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Follicular hybrid cysts with infundibular, isthmic-catagen, and pilomatrical differentiation: a report of 2 patients

Cited by 13 publications

References 15 publications

A Rare Case of a Pilar Cyst With Ductal Differentiation

A Rare Case of a Pilar Cyst With Ductal Differentiation

Hybrid Follicular Cyst (Pilomatrical and Infundibular) Arising Within a Sebaceous Nevus

Tumours of Skin Appendages

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