Follicular dendritic cell sarcoma of the lung: a report of two cases highlighting its pathological features and diagnostic pitfalls

Follicular dendritic cell tumour/sarcoma: a commonly misdiagnosed tumour in the thorax

“…Although the lung is a common site for metastasis of FDCS, only seven primary cases have been reported (Table ) . We describe one further case who presented with symptoms reflecting airway compression, with incorrect presurgical diagnosis of ‘suspicious for non‐small cell carcinoma’ based on an epithelioid tumour, but with negative lung cancer‐associated markers (cytokeratins, P40, TTF‐1).…”

“…Histologically, our data are similar to those in the literature, with variable pleomorphism, mitotic activity and necrosis. 6,14,[23][24][25] Of note, a mitotic rate of 20 per 10 HPFs was seen in one case with multiple recurrences and one case that could not be resected completely due to spinal involvement, as seen in other studies where a higher mitotic rate suggests more aggressive behaviour. 25,26 Although the lung is a common site for metastasis of FDCS, 27 only seven primary cases have been reported (Table 5).…”

“…6,14,[23][24][25] Of note, a mitotic rate of 20 per 10 HPFs was seen in one case with multiple recurrences and one case that could not be resected completely due to spinal involvement, as seen in other studies where a higher mitotic rate suggests more aggressive behaviour. 25,26 Although the lung is a common site for metastasis of FDCS, 27 only seven primary cases have been reported (Table 5). 6,14,[23][24][25]28 We describe one further case who presented with symptoms reflecting airway compression, with incorrect presurgical…”

“…25,26 Although the lung is a common site for metastasis of FDCS, 27 only seven primary cases have been reported (Table 5). 6,14,[23][24][25]28 We describe one further case who presented with symptoms reflecting airway compression, with incorrect presurgical…”

Genomic profile of pulmonary follicular dendritic cell sarcoma: a case report and systematic review

“…Here we report a rare neoplasm, which is the ninth case of primary pulmonary FDCS in English publication [5][6][7][8][9][10][11] (Table 1). In our case, the initial speculation was synovial sarcoma, which is composed of epithelial or spindle cells and is positive for EMA, CK, BCL-2, vimentin etc [12].…”