Follicular dendritic cell sarcoma of the porta hepatis

Patel, Jigar; Piper, James; Wang, Brant G.

doi:10.1136/bcr-2017-223232

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…The liver is an organ commonly involved in the development of extranodal FDCS. Primary FDCS of the liver constitutes less than 0.1% of primary liver neoplasms[2], and only a small number of single cases, as well as case series, have been reported to date.…”

Section: Introductionmentioning

confidence: 99%

Primary hepatic follicular dendritic cell sarcoma: A case report

Chen

Shen

Liu

2019

WJCC

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BACKGROUND Follicular dendritic cell sarcoma (FDCS) is an uncommon type of tumor with low incidence. To date, no standard treatment for the disease has been established. Surgery remains the main treatment. Adjuvant chemotherapy and radiotherapy are optional approaches. Metastatic cases require multidisciplinary collaborative treatments. However, the choice of chemotherapeutic drugs is controversial. CASE SUMMARY A 66-year-old Chinese woman presented to our hospital complaining of intermittent pain of right upper quadrant. An enhanced computed tomography (CT) scan of the abdomen revealed hepatocellular carcinoma. Subsequently, the patient underwent a radical partial hepatectomy. Primary FDCS of the liver was diagnosed pathologically. Except for regular follow-up examinations, the patient did not receive adjuvant chemotherapy or radiotherapy. However, fluorine-18-fluorodeoxyglucose positron emission tomography/CT (PET/CT) confirmed lymph node metastases in the space of ligamentum hepatogastricum and pancreatic head, as well as the portacaval space. The patient was given systemic chemotherapy with gemcitabine and docetaxel for she was unsuitable for surgery. Satisfactorily, the metastatic lymph nodes were significantly reduced to clinical complete remission after eight cycles of chemotherapy. Then, strengthened radiotherapy was followed when the patient rejected the opportunity of surgery. Eventually, the carcinoma got better control and the patient was free of progression. CONCLUSION This case highlights the importance of making suitable chemotherapy regimens for the rare tumor. The combination of gemcitabine, docetaxel, and consolidated radiotherapy may offer a new promising option for the treatment of metastatic hepatic FDCS in the future.

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Section: Introductionmentioning

confidence: 99%

Primary hepatic follicular dendritic cell sarcoma: A case report

Chen

Shen

Liu

2019

WJCC

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“…The FDC sarcoma can recur in about 40-50% of cases and can metastasize in about 20% of cases despite its otherwise indolent behavior. 3,32,33 The most frequent sites of metastasis are lung, liver, and lymph nodes. 12 There is no consensus on the management of FDC sarcoma.…”

Section: Journal Of Clinical and Experimental Hepatologymentioning

confidence: 99%

Hepatic Follicular Dendritic Cell Sarcoma with Epithelioid Morphology: Histopathologist's Perspective

Panigrahi

Nayak

Patra

et al. 2022

Journal of Clinical and Experimental Hepatology

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Follicular dendritic cell (FDC) sarcoma is an uncommon tumor of the liver with only 30 previous cases reported in the English literature. Histopathological examination is the gold standard for the diagnosis of FDC sarcoma although the diagnosis is often missed because of its rarity. It usually presents with spindle-cell morphology although epithelioid/biphasic morphology is also well-known. This morphological variation can also pose a diagnostic challenge. We discuss a case of unresectable hepatic FDC sarcoma in an adult male who was diagnosed in core biopsy. We highlight the relevant histomorphological differentials and diagnostic approaches to FDC sarcoma in this anecdote. ( J CLIN EXP HEPATOL xxxx;xxx:xxx)

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Follicular dendritic cell sarcoma of the porta hepatis

Cited by 2 publications

References 9 publications

Primary hepatic follicular dendritic cell sarcoma: A case report

Primary hepatic follicular dendritic cell sarcoma: A case report

Hepatic Follicular Dendritic Cell Sarcoma with Epithelioid Morphology: Histopathologist's Perspective

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