Follicular degeneration in the ovaries of goats experimentally infected with Trypanosoma vivax from the Brazilian semi-arid region

Rodrigues, Carla Monadeli Filgueira; Olinda, Robério Gomes; Silva, Taciana M. F.; Vale, Rodolfo Gurgel; Silva, Anderson E. da; Lima, Gabriela Liberalino; García, Herakles A.; Teixeira, Marta Maria Geraldes; Batista, Jael Soares

doi:10.1016/j.vetpar.2012.08.001

Cited by 24 publications

(36 citation statements)

References 33 publications

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“…These findings according to the study were suggested to be contributory to the observed anoestrus in infected does. It is however not clear if the reduction in the concentration of oestradiol observed in that study has any relationship with degeneration of ovarian follicles reported by Rodriguez et al (2013) in T. vivaxinfected goats; but Reincke et al (1998) had reported polyglandular endocrine failure by local inflammation of the pituitary and gonadal glands in trypanosomosis. Although, trypanosomes were not clearly demonstrated in the adenohypophysis, inflammation and disruption of tissue architecture as observed in this study could have been precipitated by direct presence of T. brucei as reported by Damayanti (1998).…”

Section: Discussionmentioning

confidence: 65%

Histopathological changes in some reproductive and endocrine organs of Trypanosoma brucei infected West African dwarf goat does

Leigh¹,

Emikpe²,

Ogunsola³

2015

BJVM

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Section: Discussionmentioning

confidence: 65%

Histopathological changes in some reproductive and endocrine organs of Trypanosoma brucei infected West African dwarf goat does

Leigh¹,

Emikpe²,

Ogunsola³

2015

BJVM

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“…In the female, there is abortion, irregular oestrus cycle, cystic degeneration of the ovary, follicular cyst, flaccidity of the uterine horn, decreased conception rate, low birth-weights and neonatal death (10,13,16,28). In addition, pregnant animals infected by trypanosomes may die before or after parturition (4,6).…”

Section: Introductionmentioning

confidence: 99%

Effects of Experimental Trypanosoma Congolense Infection on Sperm Morphology in Yankasa Rams

Okubanjo

Sekoni

Ajanusi

et al. 2015

Macedonian Veterinary Review

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The objective of the study was to determine the effect of T. congolense on the sperm morphology of Yankasa rams (YKR). Nine YKR aged 24-30 months-old were assigned into two groups of 6 infected and 3 uninfected control and were monitored for 7 weeks. The infected group of YKR was each inoculated with 1 x 10 6 T. congolense through the jugular vein, while the control group remained uninfected. The entire infected group developed trypanosomosis post infection (pi) characterized by sperm morphological abnormalities in the semen. There were significant (P<0.001) increases in the mean percentage of acrosomal, head, middle piece and tail abnormalities. Proximal and distal droplets as well detached heads were also significantly (P<0.001) increased post infection (pi). Acrosomal abnormalities, distal droplet and tail abnormalities increased from week 1 pi till the end of the study, while head abnormalities and detached heads increased from week 2 pi. Middle piece abnormalities and proximal droplets increased from week 3 and 4 pi till the end of the study respectively. The high incidence of morphological defects caused by T. congolense is capable of causing infertility from the first week pi thereby making the rams unfit for breeding at the end of the study.

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“…These reproductive changes in infected animals may have a multifactorial cause. Notably, T. vivax affects the normal metabolism of the animal, leading to a negative energy and protein balance, thereby promoting anemia, anorexia, hypoglycemia, and immunosuppression (STEPHEN, 1986;RODRIGUES et al, 2013;SILVA et al, 2013). A set of key endocrine, metabolic, and nutritional changes occur in gestating and lactating cows, with consequent effects on the general health status of the animal and subsequent reproductive efficiency (WOLTER, 1997).…”

Section: Discussionmentioning

confidence: 99%

“…Under these circumstances, the adverse effects of trypanosomiasis are apparently severe, with key pathological clinical manifestations. Rodrigues et al (2013) evaluated ovary involvement in goats experimentally infected with T. vivax. The results clearly demonstrated that infected goats showed a significantly reduced number of normal follicles and a high rate of follicular degeneration when compared with the uninfected control group.…”

Section: Discussionmentioning

confidence: 99%

Clinical evaluation and reproductive indices of dairy cows naturally infected with Trypanosoma vivax

Batista

Freitas

Silva

et al. 2017

SCA

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The present study was aimed to assess the clinical changes and reproductive indices of dairy cows naturally infected with Trypanosoma vivax in a herd located in the Central Sertão of Ceará, Brazil. For the study, 40 animals were selected from a herd consisting of 210 dairy cows, and subdivided into two groups: group I, consisting of 20 cows naturally infected with T. vivax, and group II, consisting of 20 uninfected cows. Data on the parameters of reproductive efficiency were evaluated using a farm database (Propad Profissional GP®), in which the individual reproductive characteristics of the animals were stored. Data collected both before and after the outbreak were compared. The cows from group I showed a sudden drop in milk production, mucosal pallor, depression, anorexia, and a significant increase in rectal temperature and decreased hematocrit during the parasitemia outbreak. These clinical signs of the disease disappeared over time. However, T. vivax was detected by polymerase chain reaction (PCR) in animals with a negative parasitological test one year after the occurrence. Comparison of the reproductive index data for cows from groups I and II before and after the outbreak showed significant differences in first postpartum estrus, service period, and intervals between deliveries. In addition, repetition of estrus and abortion were significantly associated with T. vivax infection. Analysis of the reproductive indices of cows in groups I and II suggests that T. vivax infection decreased the reproductive efficiency of the study cows. animais eram armazenadas em software Propad Profissional GP®, sendo as informações obtidas, comparadas tanto no período em que antecedeu o surto, quanto no que ocorreu após ele. As vacas do grupo I apresentaram durante o surto alta parasitemia, queda brusca da produção de leite, palidez de mucosas, depressão, anorexia, aumento significativo da temperatura retal e redução do hematócrito. Observou-se o desaparecimento dos sinais clínicos da enfermidade ao longo do tempo, no entanto, houve a confirmação do diagnóstico de T. vivax, através da Reação em Cadeia da Polimerase (PCR) em animais com exame parasitológico negativo um ano após a ocorrência. Quando comparados os dados dos índices reprodutivos das vacas do grupo I e do grupo II, no período em que antecedeu o surto, e no que ocorreu após o surto, verificou-se diferenças significativas para as variáveis: primeiro estro pós-parto (PCPP/dias), período de serviço (PS-dias) e intervalo entre parto/dias (IEP). Houve associação significativa das variáveis, repetições de estro e abortamento com a infecção por T. vivax. A análise dos dados dos índices reprodutivos das vacas dos grupos I e II sugere que T. vivax diminuiu a eficiência reprodutiva dos animais avaliados. Palavras-chave: Bovino. Eficiência reprodutiva. Tripanossomose.

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Follicular degeneration in the ovaries of goats experimentally infected with Trypanosoma vivax from the Brazilian semi-arid region

Cited by 24 publications

References 33 publications

Histopathological changes in some reproductive and endocrine organs of Trypanosoma brucei infected West African dwarf goat does

Histopathological changes in some reproductive and endocrine organs of Trypanosoma brucei infected West African dwarf goat does

Effects of Experimental Trypanosoma Congolense Infection on Sperm Morphology in Yankasa Rams

Clinical evaluation and reproductive indices of dairy cows naturally infected with Trypanosoma vivax

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