Folic Acid Supplement Intake and Risk of Colorectal Cancer in Women; A Case Control Study

Moazzen, Sara; Dastgiri, Saeed; Dolatkhah, Roya; Abdolahi, Hossein Mashhadi; Alizadeh, Behrooz Z.; Bock, Geertruida H. de

doi:10.5334/aogh.2664

Cited by 7 publications

(1 citation statement)

References 22 publications

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“…However, some studies found that low plasma folate was associated with lower CRC risk [ 7 , 8 ] . Whereas, other studies found no effect of folate on CRC risk at all [ [9] , [10] , [11] ]. In 2007, a randomized-control trail (RCT) was performed by Cole, Bernard F et al [ 12 ], found that 1 mg/dl intake of folic acid had no effect on reducing CRC risk, in contrast with Gao, Qin-Yan et al [ 13 ], which revealed a significant reduction in colorectal adenoma especially left-sided ones.…”

Section: Discussionmentioning

confidence: 90%

The relationship between folic acid and colorectal cancer; a literature review

Kherbek

Daoud

Soueycatt

et al. 2022

Annals of Medicine &Amp; Surgery

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Section: Discussionmentioning

confidence: 90%

The relationship between folic acid and colorectal cancer; a literature review

Kherbek

Daoud

Soueycatt

et al. 2022

Annals of Medicine &Amp; Surgery

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Impact of alcohol consumption on risk of colorectal cancer in Eastern Mediterranean Regional Office (EMRO) countries: a systematic review and meta-analysis

Keivanlou,

Amini-Salehi,

Joukar

et al. 2023

J Public Health (Berl.)

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Family history of cancer as a potential risk factor for colorectal cancer in EMRO countries: a systematic review and meta-analysis

Keivanlou,

Amini-Salehi,

Joukar

et al. 2023

Sci Rep

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The current meta-analysis aims to investigate the existing articles that evaluated the implications of a positive family history of cancer on the risk of colorectal cancer (CRC) within the EMRO countries. We employed PubMed, Scopus, and Web of Science as search databases for this study. To assess the quality of the selected articles, we utilized the Newcastle–Ottawa (NCO) checklist. In comparing the impact of a family history of cancer between the case and control groups, we computed the odds ratio (OR) along with its corresponding 95% confidence interval (CI). Finally, 27 articles were selected for meta-analysis. The result of the meta-analysis showed a significant association between the presence of a family history of CRC or any cancers and CRC (OR 2.21; 95% CI 1.54–3.17; P < 0.001, OR 1.76; 95% CI 1.27–2.42; P = 0.001, respectively). Our findings underscore the critical importance of timely screening and early identification for individuals with a family history of cancer. By fostering close coordination among healthcare facilities and actively promoting the adoption of screening methods for early detection, we have the potential to significantly reduce both mortality rates and financial burdens of CRC on the general public, ultimately leading to enhanced patient outcomes.

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Folic Acid Supplement Intake and Risk of Colorectal Cancer in Women; A Case Control Study

Cited by 7 publications

References 22 publications

The relationship between folic acid and colorectal cancer; a literature review

The relationship between folic acid and colorectal cancer; a literature review

Impact of alcohol consumption on risk of colorectal cancer in Eastern Mediterranean Regional Office (EMRO) countries: a systematic review and meta-analysis

Family history of cancer as a potential risk factor for colorectal cancer in EMRO countries: a systematic review and meta-analysis

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