Folic acid antioxidant supplementation to binge drinking adolescent rats improves hydric‐saline balance and blood pressure, but fails to increase renal NO availability and glomerular filtration rate
María del Carmen Gallego‐López,
María Luisa Ojeda,
Inés Romero‐Herrera
et al.
Abstract:Binge drinking (BD) is an especially pro‐oxidant pattern of alcohol consumption, particularly widespread in the adolescent population. In the kidneys, it affects the glomerular filtration rate (GFR), leading to high blood pressure. BD exposure also disrupts folic acid (FA) homeostasis and its antioxidant properties. The aim of this study is to test a FA supplementation as an effective therapy against the oxidative, nitrosative, and apoptotic damage as well as the renal function alteration occurred after BD in … Show more
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