“…Beyond controlling transmembrane transport, molecular machines in lipid bilayers may also serve to mediate other functions, including signal transduction, − catalysis, − and sensing applications. , Advancements in these related fields are likely to serve as inspiration for the development of molecular-machine-based transmembrane transporters. Indeed, the control of membrane incorporation, orientation, flip-flop, and residence time are common challenges within all of these areas of study.…”