2009
DOI: 10.1063/1.3078291
|View full text |Cite
|
Sign up to set email alerts
|

Focusing and spectral enhancement of a repetition-rated, laser-driven, divergent multi-MeV proton beam using permanent quadrupole magnets

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
50
0
1

Year Published

2009
2009
2020
2020

Publication Types

Select...
7
2
1

Relationship

1
9

Authors

Journals

citations
Cited by 72 publications
(51 citation statements)
references
References 16 publications
0
50
0
1
Order By: Relevance
“…In particular, we performed irradiation of biological samples (the human lung cancer cells) and delivered the lethal dose of 20 Gy in 200 shots, which was confirmed by the DNA double strand break revealed by the phosphorylated histone H2AX immunostaining method. [26] We also demonstrated focusing of the proton beam by a pair of wide acceptance-angle permanent magnet quadrupoles; [27] at the distance of 650 mm from the target, the protons with the quasi-monochromatic spectrum near 2.4 MeV formed a 3 mm × 8 mm spot. We also demonstrated the repetitive generation of quasi-monochromatic proton energy spectra with δE p /E p ≈ 1.6% employing the phase rotation method.…”
Section: Results Of Proton Accelerationmentioning
confidence: 98%
“…In particular, we performed irradiation of biological samples (the human lung cancer cells) and delivered the lethal dose of 20 Gy in 200 shots, which was confirmed by the DNA double strand break revealed by the phosphorylated histone H2AX immunostaining method. [26] We also demonstrated focusing of the proton beam by a pair of wide acceptance-angle permanent magnet quadrupoles; [27] at the distance of 650 mm from the target, the protons with the quasi-monochromatic spectrum near 2.4 MeV formed a 3 mm × 8 mm spot. We also demonstrated the repetitive generation of quasi-monochromatic proton energy spectra with δE p /E p ≈ 1.6% employing the phase rotation method.…”
Section: Results Of Proton Accelerationmentioning
confidence: 98%
“…The coupling of magnetic lenses with laser accelerators has previously been accomplished with permanent magnet quadrupoles (PMQs) where the capture of electrons [10] and protons [11,12] were demonstrated. Although PMQs are widely used in conventional accelerator beam lines to correct paraxial beams with small divergences, their magnetic field is on the order of 1 T and therefore cannot sufficiently capture highly divergent protons of more than a few MeV, let alone the 250 MeV protons necessary for proton therapy.…”
mentioning
confidence: 99%
“…Several methods have been demonstrated so far in order to reduce the beam divergence of a selected narrow part of the proton spectrum. They mainly employ permanent magnet quadrupoles [5][6][7] or a compact ion lens driven by a secondary laser beam [8], and the shaped target scheme exploiting the target self-charging during interaction [9]. However, it is not clear yet how these schemes could be extrapolated for a desirable performance in a FI scenario, where one would require the full flux of the beam to be concentrated at a small (order of mm) distance from the source.…”
mentioning
confidence: 99%